Mem Inst Oswaldo Cruz, Rio de Janeiro, 112(7) July 2017
Genome announcement and highlight
Complete plasmid sequence carrying type IV-like and type VII secretion systems from an atypical mycobacteria strain
Fundação Oswaldo Cruz-Fiocruz, Instituto Oswaldo Cruz, Laboratório de Genética Molecular de Microrganismos, Rio de Janeiro, RJ, Brasil
The genus Mycobacterium is highly diverse and ubiquitous in nature, comprehending fast- and slow-growing species with distinct impact in public health. The plasmid-mediated horizontal gene transfer represents one of the major events in bacteria evolution. Here, we report the complete sequence of a 160,489 bp circular plasmid (pCBMA213 2) from an atypical and fast-growing environmental mycobacteria. This is a unique plasmid, in comparison with the characterised mycobacteria plasmids, harboring a type IV-like and ESX-P2 type VII secretion systems. pCBMA213 2 can be further explored for evolutionary and conjugation studies as well as a tool to manipulate DNA within this bacteria genus.