Mem Inst Oswaldo Cruz, Rio de Janeiro, 112(7) July 2017
Genome announcement and highlight

Complete plasmid sequence carrying type IV-like and type VII secretion systems from an atypical mycobacteria strain

Sergio Mascarenhas Morgado+, Michel Abanto Marín, Fernanda S Freitas, Erica Lourenço Fonseca, Ana Carolina Paulo Vicente

Fundação Oswaldo Cruz-Fiocruz, Instituto Oswaldo Cruz, Laboratório de Genética Molecular de Microrganismos, Rio de Janeiro, RJ, Brasil

Page: 514-516 DOI: 10.1590/0074-02760160546
621 views 411 downloads
ABSTRACT

The genus Mycobacterium is highly diverse and ubiquitous in nature, comprehending fast- and slow-growing species with distinct impact in public health. The plasmid-mediated horizontal gene transfer represents one of the major events in bacteria evolution. Here, we report the complete sequence of a 160,489 bp circular plasmid (pCBMA213 2) from an atypical and fast-growing environmental mycobacteria. This is a unique plasmid, in comparison with the characterised mycobacteria plasmids, harboring a type IV-like and ESX-P2 type VII secretion systems. pCBMA213 2 can be further explored for evolutionary and conjugation studies as well as a tool to manipulate DNA within this bacteria genus.

Financial support: CAPES, PNPD-CAPES (fellowships), CNPq, IOC-FIOCRUZ (grants).
+ Corresponding author: sergio.morgado@ioc.fiocruz.br
Received 20 December 2016
Accepted 28 January 2017

Our Location

Memórias do Instituto Oswaldo Cruz

Av. Brasil 4365, Castelo Mourisco 
sala 201, Manguinhos, 21040-900 
Rio de Janeiro, RJ, Brazil

Tel.: +55-21-2562-1222

This email address is being protected from spambots. You need JavaScript enabled to view it.

Support Program

logo fiocruz logo governo
logo faperj logo cnpq marca capes