Mem Inst Oswaldo Cruz, Rio de Janeiro, 112(10) October 2017
Short communication

Glimpse into the genome sequence of a multidrug-resistant Acinetobacter pittii ST950 clinical isolate carrying the blaOXA-72 and blaOXA-533 genes in China

Zhi Ruan1, Yan Chen2, Jianfeng Wang3,+

1Zhejiang University, School of Medicine, Department of Clinical Laboratory, Sir Run Run Shaw Hospital, Hangzhou, Zhejiang, China
2The First Affiliated Hospital of Zhejiang Chinese Medical University, Department of General Practice, Hangzhou, Zhejiang, China
3The Affiliated Hospital of Hangzhou Normal University, Department of Respiratory Diseases, Hangzhou, Zhejiang, China

DOI: 10.1590/0074-02760170019
155 views 104 downloads

The development of carbapenem-resistant Acinetobacter species is of serious concern in the hospital settings and naturally occurring oxacillinase genes (blaOXA) have been identified in several Acinetobacter species. In this study, we report the genome sequence of A. pittii TCM178 belongs to ST950, a multidrug-resistant isolate that harbored the blaOXA-72 and blaOXA-533 genes simultaneous. The genome size was estimated to be 3,789,564 bp with 3,501 predicted coding regions, and G+C content is 37.60%. Our findings have raised awareness of the possible constitution of a reservoir for peculiar carbapenemase genes in A. pittii that may spread among other Acinetobacter species in China.

Financial support: National Natural Science Foundation of China (81401698 and 31600108), Zhejiang provincial medical and health science and technology plan (2015RCA017, 2015KYA167, 2016KYA108 and 2017KY125).
+ Corresponding author:
Received 19 January 2017
Accepted 11 May 2017

Our Location

Memórias do Instituto Oswaldo Cruz

Av. Brasil 4365, Castelo Mourisco 
sala 201, Manguinhos, 21040-900 
Rio de Janeiro, RJ, Brazil

Tel.: +55-21-2562-1222

This email address is being protected from spambots. You need JavaScript enabled to view it.

Support Program

logo fiocruz logo governo
logo faperj logo cnpq marca capes