Mem Inst Oswaldo Cruz, Rio de Janeiro, 112(10) October 2017
Glimpse into the genome sequence of a multidrug-resistant Acinetobacter pittii ST950 clinical isolate carrying the blaOXA-72 and blaOXA-533 genes in China
1Zhejiang University, School of Medicine, Department of Clinical Laboratory, Sir Run Run Shaw Hospital, Hangzhou, Zhejiang, China
2The First Affiliated Hospital of Zhejiang Chinese Medical University, Department of General Practice, Hangzhou, Zhejiang, China
3The Affiliated Hospital of Hangzhou Normal University, Department of Respiratory Diseases, Hangzhou, Zhejiang, China
The development of carbapenem-resistant Acinetobacter species is of serious concern in the hospital settings and naturally occurring oxacillinase genes (blaOXA) have been identified in several Acinetobacter species. In this study, we report the genome sequence of A. pittii TCM178 belongs to ST950, a multidrug-resistant isolate that harbored the blaOXA-72 and blaOXA-533 genes simultaneous. The genome size was estimated to be 3,789,564 bp with 3,501 predicted coding regions, and G+C content is 37.60%. Our findings have raised awareness of the possible constitution of a reservoir for peculiar carbapenemase genes in A. pittii that may spread among other Acinetobacter species in China.