MEM INST OSWALDO CRUZ, RIO DE JANEIRO, Vol. 112 | 2017
PAGES: DOI: 10.1590/0074-02760170145 Short communication
Culex quinquefasciatus from areas with the highest incidence of microcephaly associated with Zika virus infections in the Northeast Region of Brazil are refractory to the virus

Rosilainy Surubi Fernandes1, Stéphanie Silva Campos1, Paulino Siqueira Ribeiro1, Lidiane MS Raphael2, Myrna C Bonaldo2, Ricardo Lourenço-de-Oliveira1+

1Fundação Oswaldo Cruz, Instituto Oswaldo Cruz, Laboratório de Mosquitos Transmissores de Hematozoários, Rio de Janeiro, RJ, Brasil
2Fundação Oswaldo Cruz, Instituto Oswaldo Cruz, Laboratório de Biologia Molecular de Flavivírus, Rio de Janeiro, RJ, Brasil

Abstract

Zika virus (ZIKV) is widely distributed in Brazil and the Northeast Region (NE) is the most affected zone, showing the highest incidence of microcephaly associated with ZIKV congenital infections worldwide. We report attempts to infect three populations of Culex quinquefasciatus from severely affected sites in the NE and Southeast Region (SE) of Brazil with three strains of ZIKV isolated from these localities. An Aedes aegypti population from the SE was used as a positive control. All tested Cx. quinquefasciatus populations were refractory to the ZIKV isolates. For these reasons, we believe Cx. quinquefasciatus should not be considered a potential vector of ZIKV in Brazil.

Financial support: European Union’s Horizon 2020 Research and Innovation Programme (ZIKAlliance 734548), CAPES-COFECUB (799/14), FAPERJ (E-26/102.351/2013, E-26/201.335/2016), CNPq (309577/2013-6), NIH (1UO1 AI115595-01). The funders had no role in the study design, data collection, and analysis, decision to publish or preparation of the manuscript.
+ Corresponding author: This e-mail address is being protected from spambots. You need JavaScript enabled to view it.
Received 13 April 2017
Accepted 15 May 2017

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