MEM INST OSWALDO CRUZ, RIO DE JANEIRO, Vol. 112 | 2017
PAGES: DOI: 10.1590/0074-02760170260 Short communication
Metagenomic analysis reveals Hepatitis A virus in suspected yellow fever cases in Brazil

Liliane C Conteville1,+, Ana Maria B de Filippis2, Rita Maria R Nogueira2, Marcos César L de Mendonça2, Ana Carolina P Vicente1

1Fundação Oswaldo Cruz-Fiocruz, Instituto Oswaldo Cruz, Laboratório de Genética Molecular de Microrganismos, Rio de Janeiro, RJ, Brasil
2Fundação Oswaldo Cruz-Fiocruz, Instituto Oswaldo Cruz, Laboratório de Flavivírus, Rio de Janeiro, RJ, Brasil

Abstract

Using a metagenomic approach, we identified hepatitis A virus among cases of acute febrile illnesses that occurred in 2008-2012 in Brazil suspected as yellow fever. These findings reinforce the challenge facing routine clinical diagnosis in complex epidemiological scenarios.

Financial support: CNPq, FAPERJ grants (Project: E-25/010.001558/2014 - Neglected diseases).
+ Corresponding author: This e-mail address is being protected from spambots. You need JavaScript enabled to view it.
Received 4 July 2017
Accepted 11 September 2017

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