1Laboratório de Virologia Molecular, Instituto Carlos Chagas, Fundação Oswaldo Cruz, Curitiba, PR, Brasil
2Secretaria Estadual de Saúde do Rio Grande do Norte, Natal, RN, Brasil
3Instituto de Medicina Tropical, Universidade Federal do Rio Grande do Norte, Natal, RN, Brasil
In the early 2015, several cases of patients presenting symptoms of mild fever, rash, conjunctivitis and arthralgia were reported in the northeastern Brazil. Although all patients lived in a dengue endemic area, molecular and serological diagnosis for dengue resulted negative. Chikungunya virus infection was also discarded. Subsequently, Zika virus (ZIKV) was detected by reverse transcription-polymerase chain reaction from the sera of eight patients and the result was confirmed by DNA sequencing. Phylogenetic analysis suggests that the ZIKV identified belongs to the Asian clade. This is the first report of ZIKV infection in Brazil.
Financial support: FIOCRUZ, CNPq, CAPES, Fundação Araucária
Received 17 May 2015
Accepted 25 May 2015