Mem Inst Oswaldo Cruz, Rio de Janeiro, VOLUME 119 | 2024
Review

You are what you eat: a systematic review exploring the interaction between Brazilian sand flies and their vertebrate food sources

Felipe Dutra-Rêgo1,+, Michelli Santos da Silva2,3, Ana Paula Isnard1, Jansen Fernandes Medeiros3,4, José Dilermando Andrade Filho1, Mariana Lourenço Freire5

1Fundação Oswaldo Cruz-Fiocruz, Instituto René Rachou, Grupo de Estudos em Leishmanioses, Belo Horizonte, MG, Brasil
2Universidade Federal de Rondônia/Fundação Oswaldo Cruz-Fiocruz, Programa de Pós-Graduação em Biologia Experimental, Porto Velho, RO, Brasil
3Fundação Oswaldo Cruz-Fiocruz, Laboratório de Entomologia, Porto Velho, RO, Brasil
4Instituto Nacional de Epidemiologia na Amazônia Ocidental, Porto Velho, RO, Brasil
5Fundação Oswaldo Cruz-Fiocruz, Instituto René Rachou, Pesquisa Clínica e Políticas Públicas em Doenças Infecto-Parasitárias, Belo Horizonte, MG, Brasil

DOI: 10.1590/0074-02760240055
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ABSTRACT

Sand flies play a crucial role as vectors of bacteria, viruses, and protists, with Leishmania being the most notable among them, transmitted to vertebrate hosts during blood feeding. Understanding the feeding behaviours of sand flies is imperative for gaining insights into their eco-epidemiological roles in the transmission of these infectious agents. This systematic review aimed to answer the question ‘What are the blood-feeding sources identified in Brazilian sand flies?’ to provide an analysis of their blood-feeding habits. The diverse range of at least 16 vertebrate orders identified as blood sources for 54 sand fly species across different geographic regions was summarised, and the factors potentially associated with the risk of bias in the included studies were analysed. The findings broaden the discussion concerning methods used to identify blood meal sources and shed light on the implications of sand fly feeding behaviours for the transmission dynamics of Leishmania.

key words: sand fly blood-feeding habits systematic review Brazil
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+ Corresponding author: felipedutra04@hotmail.com
ORCID https://orcid.org/0000-0002-2799-8267
Received 04 March 2024
Accepted 12 June 2024

HOW TO CITE
Dutra-Rêgo F, da Silva MS, Isnard AP, Medeiros JF, Andrade Filho JD, Freire ML. You are what you eat: a systematic review exploring the interaction between Brazilian sand flies and their vertebrate food sources. Mem Inst Oswaldo Cruz. 2024; 119: e240055.

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