Mem Inst Oswaldo Cruz, Rio de Janeiro, VOLUME 114 | SEPTEMBER 2019
Short communication

Lutzomyia longipalpis (Diptera: Psychodidae) Argentina-Bolivia border: new report and genetic diversity

María Gabriela Quintana1,2,3,7,+, Angélica Pech-May1,3,7, Ana Denise Fuenzalida1,2,7, José Manuel Direni Mancini2,3,7, Paola Andrea Barroso3,4, Zaida Estela Yadón1,5, Mario Zaidenberg6, Oscar Daniel Salomón1,3,7

1Instituto Nacional de Medicina Tropical, Puerto Iguazú, Misiones, Argentina
2Universidad Nacional de Tucumán, Instituto Superior de Entomología, San Miguel de Tucumán, Tucumán, Argentina
3CONICET, Buenos Aires, Argentina
4Instituto de Patología Experimental, Salta, Salta, Argentina
5Pan American Health Organization, Communicable Diseases and Environmental Determinants of Health Department, Washington, DC, USA
6Ministerio de Salud y Acción Social, Buenos Aires, Argentina
7Red de Investigación de la Leishmaniasis en la Argentina

DOI: 10.1590/0074-02760190184
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ABSTRACT

American visceral leishmaniasis (AVL) has two main scenarios of transmission as follows: scattered cases in rural areas and urban outbreaks. Urban AVL is in active dispersion from the northeastern border of Argentina-Paraguay-Brazil to the South.
The presence of Lutzomyia longipalpis was initially reported in urban environments in the northwestern border of the country. The presence of Lu. longipalpis, environmental variables associated with its distribution, and its genetic diversity were assessed in Salvador Mazza, Argentina, on the border with Bolivia. The genetic analysis showed high haplotype diversity, low nucleotide diversity, and low nucleotide polymorphism index. We discuss the hypothesis of an expanding urban population with introgressive
hybridisation of older haplogroups found in their path in natural forest or rural environments, acquiring a new adaptability to urban environments, and the possibility of changes in vector capacity.

REFERENCES
01. Salomón OD, Feliciangeli MD, Quintana MG, Afonso MMS, Rangel EF. Lutzomyia longipalpis, urbanisation and control. Mem Inst Oswaldo Cruz. 2015; 110(7): 831-46.
02. Salomón OD, Rossi G, Sosa Estani S, Spinelli G. Presencia de Lutzomyia longipalpis y situación de la leishmaniosis visceral en Argentina. Medicina (Buenos Aires). 2001; 61: 174-8.
03. Santini MS, Acosta MM, Utgés ME, Aldaz ME, Salomón OD. Presence of Lutzomyia longipalpis and Nyssomyia whitmani in Entre Rios, Argentina. Rev Inst Med Trop São Paulo. 2018; 22: 60: e55.
04. Barroso PA, Marco JD, Locatelli F, Cardozo RM, Hoyos CL, Mora MC, et al. Visceral leishmaniasis caused by Leishmania infantum in Salta, Argentina: possible reservoirs and vectors. Am J Trop Med Hyg. 2015; 93(2): 334-9.
05. Copa GN, Almazán MC, Aramayo LV, Krolewiecki AJ, Cajal SP, Juarez M, et al. Tegumentary leishmaniasis and sand flies in a border area between Argentina and Bolivia. Trans R Soc Trop Med Hyg. 2018; 113(2): 91-100.
06. Bravo AG, Quintana MG, Abril M, Salomón OD. The first record of Lutzomyia longipalpis in the Argentine northwest. Mem Inst Oswaldo Cruz. 2013; 108(8): 1071-3.
07. Bravo AG, Quintana MG, Abril M, Salomón OD. The first record of Lutzomyia longipalpis in the Argentine northwest. Mem Inst Oswaldo Cruz. 2013; 108(8): 1071-3.
08. Fernández MS, Martínez MF, Pérez AA, Santini MS, Gould IT, Salomón OD. Performance of light-emitting diode traps for collecting sand flies in entomological surveys in Argentina. J Vector Ecol. 2015; 40(2): 373-8.
09. Galati EAB. Classificação de Phlebotominae. In: EF Rangel, R Lainson, editors. Flebotomíneos do Brasil. Río de Janeiro: Fiocruz; 2003. p. 53-175.
10. Quintana MG, Fernández MS, Salomón OD. Distribution and abundance of Phebotominae, vectors of leishmaniasis in Argentina: spatial and temporal analysis at different scales. J Trop Med. 2012; 2012: 16 pp.
11. Berrozpe P, Lamattina D, Santini MS, Araujo AV, Utgés ME, Salomón OD. Environmental suitability for Lutzomyia longipalpis in a subtropical city with a recently established visceral leishmaniasis transmission cycle, Argentina. Mem Inst Oswaldo Cruz. 2017; 112(10): 674-80.
12. Szelag EA, Rosa JR, Galati EAB, Andrade Filho JD, Salomón OD. Considerations on the species complex of the Cortelezzii series (Diptera: Psychodidae) and description of Evandromyia chacuensis sp. nov., a new phlebotomine species of the Chaco Region, Argentina. J Med Entomol. 2018; 55(4): 902-9.
13. Quintana MG, Santini MS, Bravo AG, Fuenzalida AD, Acosta MM, Pech-May A, et al. Distribution, abundance, and genetic variability of Lutzomyia longipalpis (Diptera: Psychodidae) in Tartagal city, Salta, Argentina. Parasite; 2016; 23(E1): 21.
14. García AL, Parrado R, Rojas E, Delgado R, Dujardin JC, Reithinger R. Leishmaniases in Bolivia: a comprehensive review and current status. Am J Trop Med Hyg. 2009; 80(5): 704-11.
15. Coutinho-Abreu IV, Sonoda IV, Fonseca AJ, Melo MA, Balbino VQ, Ramalho-Ortigão M. Lutzomyia longipalpis s. l. in Brazil and the impact of the São Francisco River in the speciation of this sand fly vector. Parasit Vectors. 2008; 1(1): 37.
16. de Oliveira E, Casaril AE, Fernandes WS, Ravanelli MS, Medeiros MJ, Gamarra RM, et al. Monthly distribution of phlebotomine sand flies, and biotic and abiotic factors related to their abundance, in an urban area to which visceral leishmaniasis is endemic in Corumbá, Brazil. PLoS One. 2016; 11(10): e0165155.
17. de Oliveira E, Galati EAB, Oliveira AG, Rangel EF, de Carvalho BM. Ecological niche modelling and predicted geographic distribution of Lutzomyia cruzi, vector of Leishmania infantum in South America. PLoS Negl Trop Dis. 2018; 12(7): e0006684.

Financial support: This work was supported by Small Grants Programme - a joint initiative of the PAHO/TDR and the Special Programme for Research and Training in Tropical Diseases, UNICEF, UNDP, the World Bank and WHO.
+ Corresponding author: gabrieladelaquintana@gmail.com
https://orcid.org/0000-0003-0972-477X
Received 29 May 2019
Accepted 02 September 2019

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