The stepwise selection for ketoconazole resistance induces upregulation of C14-demethylase (CYP51) in Leishmania amazonensis  Valter Viana Andrade-Neto; Herbert Leonel de Matos-Guedes; Daniel Cláudio de Oliveira Gomes; Marilene Marcuzzo do Canto-Cavalheiro; Bartira Rossi-Bergmann; Eduardo Caio Torres-Santos PAGE: 416-419 | DOI: 10.1590/S0074-02762012000300018

The level of ascorbate peroxidase is enhanced in benznidazole-resistant populations of Trypanosoma cruzi and its expression is modulated by stress generated by hydrogen peroxide  Fernanda Barbosa Nogueira; Joyce Fernanda A Rodrigues; Marcos Messias S Correa; Jerônimo Conceição Ruiz; Alvaro José Romanha; Silvane Maria Fonseca Murta PAGE: 494-502 | DOI: 10.1590/S0074-02762012000400009

A study of multidrug-resistant tuberculosis in risk groups in the city of Santos, São Paulo, Brazil  Andréa Gobetti Vieira Coelho; Liliana Aparecida Zamarioli; Maria Alice Telles; Lucilaine Ferrazoli; Eliseu Alves Waldman PAGE: 760-766 | DOI: 10.1590/S0074-02762012000600009

Fast test for assessing the susceptibility of Mycobacterium tuberculosis to isoniazid and rifampin by real-time PCR  Maria Gisele Gonçalves; Lucila Okuyama Fukasawa; Rosangela Siqueira Oliveira; Maristela Marques Salgado; Lee H Harrison; Kathleen A Shutt; Claudio Tavares Sacchi PAGE: 903-908 | DOI: 10.1590/S0074-02762012000700011

Detection of Mycobacterium tuberculosis in sputum from Suruí Indian subjects, Brazilian Amazon Paulo Cesar Basta; Maraníbia AC Oelemann; Walter MR Oelemann; Leila de Souza Fonseca; Carlos EA Coimbra Jr PAGE: 581-584 | DOI: S0074-02762006000600001

In house colorimetric reverse hybridisation assay for detection of the mutation most frequently associated with resistance to isoniazid in Mycobacterium tuberculosis Mirela Verza; Raquel de Abreu Maschmann; Márcia Susana Nunes Silva; Elis Regina Dalla Costa; Marta Osório Ribeiro; Franciele Rosso; Philip Noel Suffys; EnricoTortoli; Fiorella Marcelli; Arnaldo Zaha; Maria Lucia Rosa Rossetti PAGE: 710-714 | DOI: 10.1590/S0074-02762009000500008

Detection of rifampin-resistant genotypes in Mycobacterium tuberculosis by reverse hybridization assay Raquel de A Maschmann; Mirela Verza; Marcia SN Silva; Rosa Dea Sperhacke; Marta O Ribeiro; Philip Noel Suffys; Harrison Magdinier Gomes; Enrico Tortoli; Fiorella Marcelli; Arnaldo Zaha; Maria Lucia R Rossetti PAGE: 139-145 | DOI: 10.1590/S0074-02762011000200004

New approaches in antimalarial drug discovery and development - A Review Anna Caroline C Aguiar; Eliana MM da Rocha; Nicolli B de Souza; Tanos CC França; Antoniana U Krettli PAGE: 831-845 | DOI: 10.1590/S0074-02762012000700001

Patterns of hepatitis B virus infection in Brazilian human immunodeficiency virus infected patients: high prevalence of occult infection and low frequency of lamivudine resistant mutations Michel VF Sucupira; Francisco CA Mello; Eneida A Santos; Christian Niel; Valeria C Rolla; Juçara Arabe; Selma A Gomes PAGE: 655-660 | DOI: S0074-02762006000600013

The impact of the nelfinavir resistance-conferring mutation D30N on the susceptibility of HIV-1 subtype B to other protease inhibitors André FA Santos; Marcelo A Soares PAGE: 177-181 | DOI: 10.1590/S0074-02762011000200010

Shigella in Brazilian children with acute diarrhoea: prevalence, antimicrobial resistance and virulence genes Mireille Ângela Bernardes Sousa; Edilberto Nogueira Mendes; Guilherme Birchal Collares; Luciano Amedée Péret-Filho; Francisco José Penna; Paula Prazeres Magalhães PAGE: 30-35 | DOI: 10.1590/S0074-02762013000100005

Plasmid-based controls to detect rpoB mutations in Mycobacterium tuberculosis by quantitative polymerase chain reaction-high-resolution melting Joas Lucas da Silva ; Gabriela Guimaraes Sousa Leite; Gisele Medeiros Bastos; Beatriz Cacciacarro Lucas; Daniel Keniti Shinohara; Joice Sayuri Takinami; Marcelo Miyata; Cristina Moreno Fajardo; André Ducati Luchessi; Clarice Queico Fujimura Leite; Rosilene Fressatti Cardoso; Rosario Dominguez Crespo Hirata; Mario Hiroyuki Hirata PAGE: 106-109 | DOI: 10.1590/S0074-02762013000100017

Human Immunodeficiency Virus Type 1: Drug Resistance in Treated and Untreated Brazilian Children SRR Simonetti, HG Schatzmayr, JP Simonetti PAGE: 831-837

Drug Resistance and Genotypes of Strains of Mycobacterium tuberculosis Isolated from Human Immunodeficiency Virus-infected and Non-infected Tuberculosis Patients in Bauru, São Paulo, Brazil Ida Maria Foschiani Dias Baptista, Maraníbia Cardoso Oelemann*, Diltor Vladimir Araújo Opromolla, Philip Noel Suffys* PAGE: 1147-1152

Direct Sensitivity Test of the MB/BacT System Angela Maria Werneck Barreto, Joselba Borges Melo Araujo, Reginalda Ferreira de Melo Medeiros, Paulo Cesar de Souza Caldas PAGE: 263-264

Genome Comparison of Progressively Drug Resistant Plasmodium falciparum Lines Derived from Drug Sensitive Clone Ravi Toteja, Lathika Nair, VK Bhasin PAGE: 427-433

Mutations in Plasmodium falciparum Dihydrofolate Reductase and Dihydropteroate Synthase of Isolates from the Amazon Region of Brazil KF Vasconcelos, CV Plowe, CJ Fontes, D Kyle, DF Wirth,LH Pereira da Silva, MG Zalis PAGE: 721-728

Antimalarial Drug Susceptibility Testing of Plasmodium falciparum in Brazil Using a Radioisotope Method Crispim Cerutti Junior, Christiane Marques, Filomena EC de Alencar, Rui Rafael Durlacher, Anna Alween, Aluísio AC Segurado, Lorrin W Pang, Mariano G Zalis PAGE: 803-809

Efficacy of a New Schistosomicidal Agent 2-[(methylpropyl)amino]-1-octanethiosulfuric Acid against an Oxamniquine Resistant Schistosoma mansoni Isolate Marcus Luiz de Oliveira Penido, Paulo Marcos Zech Coelho,David Lee Nelson PAGE: 811-813

Drug Resistance Patterns among Hospitalized Tuberculous Patients in Rio de Janeiro, Brazil, 1993-1994 FCO Fandinho, AL Kritski, C Hofer, H Conde Jr, RMC Ferreira, MG Silva, LS Fonseca PAGE: 543-547

Malaria on the Guiana Shield: a review of the situation in French Guiana Lise Musset, Stéphane Pelleau, Romain Girod, Vanessa Ardillon, Luisiane Carvalho, Isabelle Dusfour, Margarete SM Gomes, Félix Djossou, Eric Legrand PAGE: 525-533 | DOI: 10.1590/0074-0276140031

Activity of Oxamniquine at Skin, Pulmonary and Sexual Maturation Phases, on a Schistosoma mansoni Strain (R1) Previously Reported as Resistant at the Adult Phase Paulo Marcos Z Coelho*/**/, Fábio Ribeiro*, Rômulo T Mello, Francisco C Lima e Silva**, José Augusto Nogueira-Machado** PAGE: 267-268

Sensitivity of Leishmania spp. to Glibenclamide and 4-Aminopiridine: A Tool for the Study of Drug Resistance Development Alicia Ponte-Sucre, Yelitza Campos, Jorge Vázquez, Heidrun Moll, Alexis Mendoza-León PAGE: 601-606

A historical perspective on malaria control in Brazil Sean Michael Griffing, Pedro Luiz Tauil, Venkatachalam Udhayakumar, Luciana Silva-Flannery PAGE: 701-718 | DOI: 10.1590/0074-02760150041

Highly active ozonides selected against drug resistant malaria Lis Lobo, Bruno de Sousa, Lília Cabral, Maria LS Cristiano, Fátima Nogueira PAGE: 450-453 | DOI: 10.1590/0074-02760160077

An overview of the molecular and epidemiological features of HIV-1 infection in two major cities of Bahia state, Brazil Amanda GM Amaral, Isabele B Oliveira, Diego C Carneiro, Luiz CJ Alcantara, Joana P Monteiro-Cunha PAGE: 411-418 | DOI: 10.1590/0074-02760160458

Increased thiol levels in antimony-resistant Leishmania infantum isolated from treatment-refractory visceral leishmaniasis in Brazil Lucas S Magalhães, Lays GS Bomfim, Sthefanne G Mota, Geydson S Cruz, Cristiane B Corrêa, Diego M Tanajura, Michael W Lipscomb, Valéria M Borges, Amélia R de Jesus, Roque P de Almeida, Tatiana R de Moura PAGE: 119-125 | DOI: 10.1590/0074-02760170289

Whole genome sequence of Mycobacterium kansasii isolates of the genotype 1 from Brazilian patients with pulmonary disease demonstrates considerable heterogeneity Edson Machado, Sidra Ezidio Gonçalves Vasconcellos, Camillo Cerdeira, Lia Lima Gomes, Ricardo Junqueira, Luciana Distasio de Carvalho, Jesus Pais Ramos, Paulo Redner, Carlos Eduardo Dias Campos, Paulo Cesar de Souza Caldas, Ana Paula Chaves Sobral Gomes, Telma Goldenberg, Fatima Fandinho Montes, Fernanda Carvalho de Queiroz Mello, Vinicius de Oliveira Mussi, Elena Lasunskaia, Dick van Soolingen, Antonio Basílio de Miranda, Leen Rigouts, Bouke C de Jong, Conor J Meehan, Marcos Catanho, Philip N Suffys DOI: 10.1590/0074-02760180085

Overexpression of eukaryotic initiation factor 5A (eIF5A) affects susceptibility to benznidazole in Trypanosoma cruzi populations Douglas de Souza Moreira, Ana Paula Duarte, Fabiano Sviatopolk Mirsky Pais, Rosiane Aparecida da Silva-Pereira, Alvaro José Romanha, Sergio Schenkman, Silvane Maria Fonseca Murta DOI: 10.1590/0074-02760180162

Commercial drugs containing flavonoids are active in mice with malaria and in vitro against chloroquine-resistant Plasmodium falciparum Julia Penna-Coutinho, Anna CC Aguiar, Antoniana Ursine Krettli DOI: 10.1590/0074-02760180279

Overview of artemisinin effectiveness during outset years of its implementation in the western Brazilian Amazon Raquel de Medeiros Pinto, Vanderson de Souza Sampaio, Gisely Cardoso de Melo, Maria das Graças Costa Alecrim, Karine Mattos, Renata Trentin Perdomo, Sabrine da Costa Cordeiro, Ana Flávia Alves Parente, Lídia Raquel de Carvalho, Rinaldo Pôncio Mendes, Marcus Vinícius Guimarães Lacerda, Wuelton Marcelo Monteiro, Simone Schneider Weber DOI: 10.1590/0074-02760190075

Evaluation of drug susceptibility profile of Mycobacterium tuberculosis Lineage 1 from Brazil based on whole genome sequencing and phenotypic methods Arthur Emil dos Santos Guimarães, Abhinav Sharma, Ismari Perini Furlaneto, Liliana Rutaihwa, Jedson Ferreira Cardoso, Marília Lima da Conceição, Lizânia Borges Spinassé, Edson Machado, Maria Luiza Lopes, Rafael Silva Duarte, Sebastien Gagneux, Philip Noel Suffys, Karla Valéria Batista Lima, Emilyn Costa Conceição DOI: 10.1590/0074-02760200520

Antioxidant defence system as a rational target for Chagas disease and Leishmaniasis chemotherapy Ana Maria Murta Santi, Silvane Maria Fonseca Murta DOI: 10.1590/0074-02760210401

Leishmania spp. genetic factors associated with cutaneous leishmaniasis antimony pentavalent drug resistance: a systematic review Raphaela Lisboa Andrade Nery, Thaline Mabel Sousa Santos, Luana Leandro Gois, Aldina Barral, Ricardo Khouri, Caroline Alves Feitosa, Luciane Amorim Santos DOI: 10.1590/0074-02760230240