SARS-CoV-2 diagnostic diary: from rumors to the first case. Early reports of molecular tests from the military research and diagnostic institute of Rio de Janeiro Marcio da Costa Cipitelli, Elizabeth Valentin, Nadia Vaez Gonçalves da Cruz, Tatiana LS Nogueira, Elaine Cristina Amaro de Melo, Rebeca Araujo da Silva, Marcelo M Serra, André L Meriano, Alberto ML Colares, Marcos Dornelas-Ribeiro, Caleb GM Santos DOI: 10.1590/0074-02760200200

Low risk of serological cross-reactivity between dengue and COVID-19  Michele Spinicci, Alessandro Bartoloni, Antonia Mantella, Lorenzo Zammarchi, Gian Maria Rossolini, Alberto Antonelli DOI: 10.1590/0074-02760200225

Flavonoid glycosides and their putative human metabolites as potential inhibitors of the SARS-CoV-2 main protease (Mpro) and RNA-dependent RNA polymerase (RdRp) Felipe Moura A da Silva, Katia Pacheco A da Silva, Luiz Paulo M de Oliveira, Emmanoel V Costa, Hector HF Koolen, Maria Lúcia B Pinheiro, Antonia Queiroz L de Souza, Afonso Duarte L de Souza DOI: 10.1590/0074-02760200207

Genomic and phylogenetic characterisation of an imported case of SARS-CoV-2 in Amazonas State, Brazil Valdinete Alves do Nascimento, André de Lima Guerra Corado, Fernanda Oliveira do Nascimento, Ágatha Kelly Araújo da Costa, Debora Camila Gomes Duarte Sérgio Luiz Bessa Luz, Luciana Mara Fé Gonçalves, Michele Silva de Jesus, Cristiano Fernandes da Costa, Edson Delatorre, Felipe Gomes Naveca DOI: 10.1590/0074-02760200310

Comparison of viral load between saliva and nasopharyngeal swabs for SARS-CoV2: the role of days of symptoms onset on diagnosis Alberto Fernando Oliveira Justo, Mariana Sardinha Bueno, Gabriela Rodrigues Barbosa, Ana Helena Perosa, Joseane MA Carvalho, Nancy Bellei DOI: 10.1590/0074-02760210018

SARS-CoV-2 isolation from the first reported patients in Brazil and establishment of a coordinated task network Danielle Bastos Araujo, Rafael Rahal Guaragna Machado, Deyvid Emanuel Amgarten, Fernanda de Mello Malta, Gabriel Guarany de Araujo, Cairo Oliveira Monteiro, Erika Donizetti Candido, Camila Pereira Soares, Fernando Gatti de Menezes, Ana Carolina Cornachioni Pires, Rúbia Anita Ferraz Santana, Amanda de Oliveira Viana, Erick Dorlass, Luciano Thomazelli, Luis Carlos de Sousa Ferreira, Viviane Fongaro Botosso, Cristiane Rodrigues Guzzo Carvalho, Danielle Bruna Leal Oliveira, João Renato Rebello Pinho, Edison Luiz Durigon DOI: 10.1590/0074-02760200342

Prevention and Control of Aedes transmitted infections in the post-pandemic scenario of COVID-19: challenges and opportunities for the region of the Americas Héctor Gómez Dantés, Pablo Manrique-Saide, Gonzalo Vazquez-Prokopec, Fabian Correa Morales, João Bosco Siqueira Junior, Fabiano Pimenta, Giovanini Coelho, Haroldo Bezerra DOI: 10.1590/0074-02760200284

Coagulation modifiers targeting SARS-CoV-2 main protease Mpro for COVID-19 treatment: an in silico approach Ísis Venturi Biembengut , Tatiana de Arruda Campos Brasil de Souza DOI: 10.1590/0074-02760200179

Identification of SARS-CoV-2 and additional respiratory pathogens cases under the investigation of COVID-19 initial phase in a Brazilian reference laboratory Aline da Rocha Matos, Fernando Couto Motta, Braulia Costa Caetano, Maria Ogrzewalska, Cristiana Couto Garcia, Jonathan Christian Oliveira Lopes, Milene Miranda, Miriam Teresinha Furlam Prando Livorati, André Abreu, David Brown, Marilda Mendonça Siqueira DOI: 10.1590/0074-02760200232

COVID-19: molecular targets, drug repurposing and new avenues for drug discovery Mario Roberto Senger, Tereza Cristina Santos Evangelista, Rafael Ferreira Dantas, Marcos Vinicius da Silva Santana, Luiz Carlos Saramago Gonçalves, Lauro Ribeiro de Souza Neto, Sabrina Baptista Ferreira, Floriano Paes Silva-Junior DOI: 10.1590/0074-02760200254

Should COVID-19 be branded to Viral Thrombotic Fever? [ACCEPTED ARTICLES / PRELIMINARY VERSION] Costa-Filho, RC; Castro-Faria-Neto, HC; Mengel, J; Pelajo-Machado, M; Martins, MA; Leite, ET; Mendonça-Filho, HTF; Brasil de Souza,TAC; Bentacor, GB ;Leite Gagliardi, JP DOI: 10.1590/0074-02760200552

Should COVID-19 be branded to viral thrombotic fever? Rubens Carmo Costa-Filho, Hugo Caire Castro-Faria Neto, José Mengel, Marcelo Pelajo-Machado, Marco Aurélio Martins, Érica Távora Leite, Hugo Tannus Mendonça-Filho, Tatiana de Arruda Campos Brasil de Souza, Gonzalo Bello Bentacor, José Paulo Gagliardi Leite DOI: 10.1590/0074-02760200552

HIV/Aids and COVID-19 in Brazil: in four decades, two antithetical approaches to face serious pandemics Bernardo Galvão-Castro, Maria Fernanda Rios Grassi, Euclides Ayres de Castilho, Dirceu Bartolomeu Greco DOI: 10.1590/0074-02760210071

SARS-CoV-2 variant N.9 identified in Rio de Janeiro, Brazil Luis Fernando Lopez Tort, Ieda Pereira Ribeiro, Lidiane Souza Raphael Menezes, Alexandre Araújo Cunha dos Santos, Marta Pereira Santos, Luana Damasceno, Paola Cristina Resende Silva, Marilda Agudo Mendonça Teixeira de Siqueira, Patricia Brasil, Myrna Cristina Bonaldo DOI: 10.1590/0074-02760210166

The promising drugs included in WHO’s Solidarity Project: a choice based in scientific knowledge and institutional competencies Andréia Cristina Galina, Deise Sarzi, Larissa Campos de Medeiros, André Luiz Franco Sampaio, Jacqueline Leta DOI: 10.1590/0074-02760200603

Identification and characterization of SARS-CoV-2 and Human alphaherpesvirus 1 from a productive coinfection in a fatal COVID-19 case Alice Laschuk Herlinger, Fábio Luís Lima Monteiro, Mirela D’arc, Filipe Romero Rebello Moreira, Harrison James Westgarth, Rafael Mello Galliez, Diana Mariani, Luciana Jesus da Costa, Luiz Gonzaga Paula de Almeida, Carolina Moreira Voloch, Covid19-UFRJ Workgroup, Adriana Suely de Oliveira Melo, Renato Santana de Aguiar, André Felipe Andrade dos Santos, Terezinha Marta Pereira Pinto Castiñeiras, Ana Tereza Ribeiro de Vasconcelos, Esaú Custódio João Filho, Claudia Caminha Escosteguy, Orlando da Costa Ferreira Junior, Amilcar Tanuri, Luiza Mendonça Higa DOI: 10.1590/0074-02760210176

Open-source real-time quantitative RT-PCR-based on a RNA standard for the assessment of SARS-CoV-2 viral load Juliana Comerlato, Carolina Baldisserotto Comerlato, Fernando Hayashi Sant’Anna, Marina Bessel, Celina Monteiro Abreu, Eliana Márcia Wendland DOI: 10.1590/0074-02760210237

First report and genome sequencing of SARS-CoV-2 in a cat (Felis catus) in Colombia Yesica Botero, Juan David Ramírez, Héctor Serrano-Coll, Ader Aleman, Nathalia Ballesteros, Caty Martinez, Marina Muñoz, Alfonso Calderon, Luz H Patiño, Camilo Guzman, Sergio Castañeda, Yonairo Hererra, Salim Mattar DOI: 10.1590/0074-02760210375

COVID-19 outbreaks among crew members in non-cruise vessels anchoring in Salvador, Brazil, 2021 Cristiane Wanderley Cardoso, Mirela Maisa da Silva Souza, Ana Claudia Venegeroles de Sá Teles, Hernan Dario Argibay, Olivete Borba dos Reis, Felicidade Mota Pereira, Marta Giovanetti, Tereza Magalhaes, Guilherme Sousa Ribeiro DOI: 10.1590/0074-02760220114

Coagulopathy and the humoral response against viral proteins in patients at different stages of COVID-19 Fernanda Pereira Monteiro, Victor de Souza Tavares, Rayane da Silva Oliveira Souza, Larissa Paola Rodrigues Venâncio, Mary Hellen Fabres-Klein, Rodrigo Feliciano do Carmo, Raphael Contelli Klein, Jonilson Berlink Lima, Théo Araújo-Santos DOI: 10.1590/0074-02760220072

A straightforward one-step strategy for SARS-CoV-2 diagnosis and screening of variants of concern: a multicentre study Marcela Fontana-Maurell, Fernando do Couto Motta, Monica Barcellos Arruda, Pedro Cardoso, Marisa Ribeiro, Elisabete Andrade, Daniela T Godoy, Elaine Costa, Daniele Rocha, Paola Cristina Resende, Marilda Agudo MT Siqueira, Rodrigo Brindeiro, Patrícia Alvarez, The collaborative study group DOI: 10.1590/0074-02760220202

Point-of-care testing for COVID-19: a simple two-step molecular diagnostic development and validation during the SARS-CoV-2 pandemic Andre Akira Gonzaga Yoshikawa, Sabrina Fernandes Cardoso, Lívia Budziarek Eslabão, Iara Carolini Pinheiro, Priscila Valverde, Gisele Caminha, Oscar Bruna Romero, Leandro Medeiros, Luísa Damazio Pitaluga Rona, André Nóbrega Pitaluga DOI: 10.1590/0074-02760230236