Editorial

Opening the conversation in peer review, finally Adeilton Alves Brandão, Ana Carolina P Vicente DOI: 10.1590/0074-02760250005

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Reviews

Congenital Zika virus infection in laboratory animals: a comparative review highlights translational studies on the maternal-foetal interface Noemi Rovaris Gardinali, Renato Sergio Marchevsky, Yara Cavalcante Vieira, Marcelo Pelajo-Machado, Tatiana Kugelmeier, Juliana Gil Melgaço, Márcio Pinto Castro, Jaqueline Mendes de Oliveira, Marcelo Alves Pinto DOI: 10.1590/0074-02760240125

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Understanding the genetic complexity of Leishmania infantum in the Americas: a focus on 3’NT/NU gene deletion Monique Florêncio, Elisa Cupolillo, Mariana Côrtes Boité DOI: 10.1590/0074-02760240160

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Use of Brazilian flora as the main source of new antimalarials: a systematic review Ana Rafaela Antunes Porto, Isabela de Brito Duval, Luisa Vitor Braga do Amaral, Izabela da Silva Oliveira, João Gabriel Acioli de Siqueira, Bruno Araújo de Albuquerque, Maria Alice Guarini Rocha, Gabriela Gomes Monteiro Lemos, Marcelo Eduardo Cardozo, José Bryan da Rocha Rihs, Ricardo Toshio Fujiwara, Ana Laura Grossi de Oliveira, Ramayana Morais de Medeiros Brito, Lilian Lacerda Bueno DOI: 10.1590/0074-02760240123

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Beyond the first case of Chagas disease: the Berenice strain as a model for understanding long-term Trypanosoma cruzi infection Diana Bahia, André Guilherme da Costa-Martins, Werica Bernardo Pereira, Fernanda Sycko Marchiano, Camila Miyagui Yonamine, José Franco da Silveira DOI: 10.1590/0074-02760240291

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Role of the epitranscriptome in viral infections: beneficial or detrimental? Muhammad Fawwaz Abdullah, Kok Sing Yee, Nurhafiza Zainal, Sazaly AbuBakar, Chin Kim Ling DOI: 10.1590/0074-02760250055

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The Deanes’ malarias and the antimalarial drugs in 1939 and the 1940s† Francisco José Roma Paumgartten, Ana Cecilia Amado Xavier de Oliveira, Cláudio Tadeu Daniel-Ribeiro DOI: 10.1590/0074-02760250232

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One health and the ecology of Leprosy: the potential role of wildlife, environment, and arthropods in Mycobacterium leprae transmission ACCEPTED ARTICLES / PRELIMINARY VERSION Nicole Rodrigues Araujo, Yasmin Silva Forte, Flavio Alves Lara, Diego Augusto Souza Oliveira DOI: 10.1590/0074-02760250304

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Perspectives

Non-cerebral malaria: does such a thing exist? Beatriz Nogueira Siqueira-e-Silva, Luciana Pereira de Sousa, Pamela Rosa-Gonçalves, Rízia Maria da Silva, Yuri Chaves Martins, Patrícia Brasil, Cláudio Tadeu Daniel-Ribeiro DOI: 10.1590/0074-02760240223

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Challenges in developing new tuberculosis vacines Gabriela Sadigurschi, Maria Cristina Caetano Kuschnir, Ewerton Alves Portela dos Santos, Bruno Rangel Antunes da Silva, Celia Menezes Cruz Marques, Raissa Coelho de Andrade, Clarice Monteiro Vianna, Danillo Gonçalves de Barros, Mariana Torres Mazzi, Elvira Alonso Lago, Eliane Matos dos Santos, Maria de Lourdes de Sousa Maia DOI: 10.1590/0074-02760240236

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Chagas disease in Brazil: new challenges and perspectives for old problems Fred Luciano Neves Santos, Veruska Maia da Costa, Rafaella Albuquerque e Silva DOI: 10.1590/0074-02760240279

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The 50th Anniversary Conference – Caxambu 2024 Renata Rosito Tonelli, Daniel José Galafasse Lahr, Elvira Maria Saraiva, Angela Hampshire de Carvalho Santos Lopes DOI: 10.1590/0074-02760250061

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Chagas disease and Brazil’s unified health system (SUS): the challenge of confronting historical gaps ACCEPTED ARTICLES / PRELIMINARY VERSION Filipe Anibal Carvalho-Costa, Dilma do Socorro Moraes de Souza, Lívia Dórea Dantas Fernandes, João Marcos Barbosa-Ferreira, Jorge Augusto de Oliveira Guerra, Pedro Albajar Viñas, Angela Cristina Verissimo Junqueira DOI: 10.1590/0074-02760250322

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Malaria, anemia, and hospitalizations among Yanomami children in Roraima, brazilian Amazon: the perspective of hemotherapy professionals ACCEPTED ARTICLES / PRELIMINARY VERSION Filipe Anibal Carvalho-Costa, Daniela Ribeiro Roque, Fabiana Granja DOI: 10.1590/0074-02760250336

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Unseen, untreated: chronic Giardia lamblia infections and the gaps in health systems ACCEPTED ARTICLES / PRELIMINARY VERSION Filipe Anibal Carvalho-Costa, Alda Maria Da-Cruz, Deiviane Aparecida Calegar, Maria Fantinatti DOI: 10.1590/0074-02760250251

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Research Articles

Surveillance of land molluscs infected by Angiostrongylus cantonensis (Nematoda) reveals risk areas for zoonotic eosinophilic meningitis in the State of Rio de Janeiro, Brazil Paulo Sergio Rodrigues, Suzete Rodrigues Gomes, Jucicleide Ramos-de-Souza, Monica Ammon Fernandez, Arnaldo Maldonado-Junior, Silvana Carvalho Thiengo DOI: 10.1590/0074-02760240011

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Immunogenic mapping of potential epitopes from Tc-CTL-1 for the diagnosis of murine toxocariasis Gabriela Rodrigues e Fonseca, Ana Laura Grossi de Oliveira, Ramayana Morais de Medeiros Brito, Marcelo Andreetta Corral, Richard John Ward, Pâmela Aparecida de Lima, José Bryan da Rocha Rihs, Marcelo Eduardo Cardozo, Paula Keiko Sato, Ricardo Toshio Fujiwara, Sergio Vieira dos Santos, Ronaldo Cesar Borges Gryschek, Susana Angelica Zevallos Lescano DOI: 10.1590/0074-02760240111

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Silent dissemination of HTLV-1: evidence of intrafamilial transmission in a Brazilian reference centre Daniele Leite Alves, Roberta Muniz Luz Silva, João Pedro Melo de Freitas Santos, Rebeca Leão Amorim, Carolina Souza Santana, Felipe de Oliveira Andrade, Saadia Oliveira Ribeiro, Giselle Calasans de Souza Costa, Luciane Amorim Santos, Davi Tanajura Costa, Fernanda Khouri Barreto DOI: 10.1590/0074-02760240191

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Investigation of the activity of 4-aminoquinolines as cysteine protease inhibitors with application in the treatment of Chagas disease Rahamah Sheu-Idrees, Gabriel Vitor de Lima Marques, Pedro Augusto Lemos Santana, Lucas Abreu Diniz, Daniela de Melo Resende, Saidi Odoma, Omodamiro Olorunshola, Rafaela Salgado Ferreira, Silvane Maria Fonseca Murta, Vinícius Gonçalves Maltarollo, Renata Barbosa de Oliveira DOI: 10.1590/0074-02760240161

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Pharmacokinetics of two pharmaceutical presentations of benznidazole in adult Trypanosoma cruzi infected population Yolanda Hernández, María Elena Marson, Marisa Liliana Fernández, Omar Sued, Claudia Frola, Santiago Perez Lloret, Pedro Cahn, Nilda Graciela Prado, Guido Enrique Mastrantonio Garrido, Sergio Sosa-Estani DOI: 10.1590/0074-02760240177

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Looking for approved-medicines to be repositioned as anti-Trypanosoma cruzi agents. Identification of new chemotypes with good individual- or in combination-biological behaviours Claudia Veira, Diego Benítez, Leticia Pérez-Díaz, Guzmán Álvarez, Hugo Cerecetto, Elena Aguilera DOI: 10.1590/0074-02760240183

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Impact of dengue virus infection on the cytoadherence of Plasmodium vivax-infected erythrocytes Maria Geuziane Soares da Cruz, Rafaella Oliveira dos Santos, Maria Gloria Teixeira Sousa, Fabio TM Costa, Marcus Vinícius Guimarães de Lacerda, Stefanie Costa Pinto Lopes, Pritesh Lalwani DOI: 10.1590/0074-02760240185

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Concomitant occurrence of chronic Schistosoma mansoni infection and chronic colitis restore immune imbalance and dysbiosis leading to protection against intestinal colitis and schistosome egg-induced intestinal fibrosis You-Ren Lin, Long Yin Lam, Chun-Ming Chang, Ho Yin Pekkle Lam DOI: 10.1590/0074-02760240045

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Cross-sectional entomological monitoring combined with professional qualifications in transition areas for yellow fever and autochthonous malaria in the Atlantic Forest in Rio de Janeiro, Brazil Claulimara Lopes Moreira, Izabel Cristina dos Reis, Daniel Cardoso Portela Câmara, Tania Ayllón, Mariana Dionizio Machado, Agostinho Cardoso Nascimento-Pereira, Jefferson Pereira Caldas dos Santos, Nathan Burkett-Cadena, Nildimar Alves Honório DOI: 10.1590/0074-02760240139

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Vibrio cholerae and Vibrio paracholerae bacteraemia strains encompass lineages that share resistome and virulome profiles Sergio Mascarenhas Morgado, Erica Lourenço da Fonseca, Ana Carolina Paulo Vicente DOI: 10.1590/0074-02760240159

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In silico construction of a multi-epitope vaccine (RGME-VAC/ATS-1) against the Rickettsia genus using immunoinformatics Andrei Giacchetto Felice, Thaís Cristina Vilela Rodrigues, Pedro Henrique Marques, Felipe Lucas Zen, Marcela Rezende Lemes, Rafael Obata Trevisan, Bruno Silva Andrade, Carlo José Freire de Oliveira, Vasco Ariston de Carvalho Azevedo, Sandeep Tiwari, Siomar de Castro Soares DOI: 10.1590/0074-02760240201

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Effect of temperature on the activity of efflux pumps in selected species of human opportunistic bacterial pathogens Dušan Hurto?, Lukáš Hleba, Jana Petrová, Maroš Laho, Ján Kore?, Adriana Liptáková DOI: 10.1590/0074-02760240162

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Aedes aegypti reproductive aspects: constant light significantly affects the embryonic development Luana Cristina Farnesi, Gabrielle da Silva Oliveira Alves, Luciana Ordunha Araripe, Rafaela Vieira Bruno DOI: 10.1590/0074-02760240233

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First record of natural infection by Angiostrongylus cantonensis (Nematoda: Metastrongyloidea) in Tanychlamys indica (Godwin-Austen, 1883) in the city of São Paulo, Brazil Dan Jessé Gonçalves da Mota, Sylvio Cesar Rocco, Liliane Ré Di Luca, Jailson Apóstolo dos Santos, Eliana Fernandes Pavani Werneck, Amanda de Oliveira Baccin, Ricardo Gava, Vera Lucia Pereira-Chioccola, Leyva Cecília Vieira de Melo DOI: 10.1590/0074-02760240192

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Mapping special areas of the Brazilian National Malaria Control Program in the Amazon region: a territorial-based approach to surveillance Hermano Gomes Albuquerque, Gerusa Belo Gibson Santos, Alexandre San Pedro Siqueira, Ronan Rocha Coelho, Jefferson Pereira Caldas Dos Santos, Heitor Levi Ferreira Praça, Paulo Cesar Peiter, Leandro Henrique Vouga Pereira, Joseli Oliveira-Ferreira, Martha Cecilia Suárez Mutis DOI: doi: 10.1590/0074-02760240068

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Prognostic value of soluble TNF receptors in Chagas cardiomyopathy: observational study Matheus Ribeiro Ávila, Daniel Menezes de Souza, Lucas Fróis Fernandes de Oliveira, Pedro Henrique Scheidt Figueiredo, Liliany Mara Carvalho Silva, Whesley Tanor Silva, Mauro Felippe Felix Mediano, Leonardo Augusto da Costa Teixeira, Luciano Fonseca Lemos de Oliveira, Marcus Alessandro de Alcantara, Sanny Cristina de Castro Faria, Arthur Nascimento Arrieiro, Vanessa Amaral Mendonça, Ana Cristina Rodrigues Lacerda, Henrique Silveira Costa DOI: 10.1590/0074-02760240107

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Heterochromatin protein 1 (HP1) of Schistosoma mansoni: non-canonical chromatin landscape and oviposition effects Natália Silva da Trindade, Marilia Bergamini Valentini, Anne Rognon, Tiago Manuel Fernandes Mendes, Matheus de Souza Gomes, Silmara Marques Allegretti, Christoph Grunau, Fernanda Janku Cabral DOI: 10.1590/0074-02760240075

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Acute Chagas disease in Amazonia, western Pará: perspectives from medical assistance to genetic elucidation Helena Rangel Esper, Vera Lúcia Teixeira de Freitas, João Guilherme Pontes Lima Assy, Olívia Campos Pinheiro Berreta, Alisson dos Santos Brandão, Erika Yoshie Shimoda Nakanishi, Claudia de Abreu Fonseca, Francisco Oscar de Siqueira França, Marta Heloísa Lopes DOI: 10.1590/0074-02760240108

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Exploring BCG to deliver avidin fusion antigens from Schistosoma mansoni Lais Sayuri Yamamoto, Monalisa Martins Trentini, Dunia Rodriguez, Paulo Henrique Santana Silveira, Arthur Daniel Januzzi, Ana Carolina de Oliveira Carvalho, Luciana Cezar de Cerqueira Leite, Alex Issamu Kanno DOI: 10.1590/0074-02760240167

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Leukocyte telomere length and telomerase activity in Long COVID patients from Rio de Janeiro, Brazil Giane Gonçalves dos Reis, Rafaele Tavares Silvestre, Gilda Alves, Lucas Delmonico, Mariana Chantre-Justino, Aline dos Santos Moreira, Beatriz de Lima Alessio Müller, Carolina Ramos do Nascimento, Denzel Luis Pereira da Silva, Louisy Sanches dos Santos, Ana Luíza de Mattos-Guaraldi, Maria Helena Ornellas DOI: 10.1590/0074-02760240129

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Agglomerative hierarchical cluster analysis and temporal trend of leprosy indicators in Brazilian states, 2012-2022 Lúcia Rolim Santana de Freitas, Fernanda Fernandez Nóbrega DOI: 10.1590/0074-02760240163

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Pandemic ST131 Escherichia coli presenting the UPEC/EAEC and ExPEC/EAEC hybrid pathotypes recovered from extraintestinal infections in a clinical setting of the Brazilian Amazon region Nathália MS Bighi, Érica Lourenço Fonseca, Fernanda S Freitas, Sergio Mascarenhas Morgado, Ana Carolina Paulo Vicente DOI: 10.1590/0074-02760240204

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Lessons from the “Urbanorum spp.” controversy: a supposed parasite and the need for scientific rigor and quality research in Latin America Diego Fernando Echeverry, Manuel Andrés Sarria, Gloria Inés Palma DOI: 10.1590/0074-02760240144

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Single nucleotide polymorphisms in IFN-gamma, TNF-alpha, IL-6, IL-10, and TGF-beta in pulmonary and extrapulmonary tuberculosis in the State of Ceará, northeastern Brazil Roberta dos Santos Silva Luiz, Thales Alves Campelo, Caroliny Soares Silva, Lucas de Lima Nogueira, Soraya de Oliveira Sancho, Ana Karolliny Alves da Silva, Cristiane Cunha Frota, Filipe Anibal Carvalho-Costa DOI: 10.1590/0074-02760240147

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Parasitological cure and clinical benefits of benznidazole treatment in patients from the Jequitinhonha Valley, MG, Brazil, with recent chronic infection by Trypanosoma cruzi II Marta de Lana, Lourena Tomazelli Suave, Júlio César Santoro de Oliveira Assis, Girley Francisco Machado de Assis, Matheus Marques Milagre, Glaucia Diniz Alessio, Renato Afonso Salgado, Olindo Assis Martins-Filho, Pedro Albajar-Viñas, Rosália Morais Torres DOI: 10.1590/0074-02760240229

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Miltefosine analogues with comparable antileishmanial activity and significantly reduced macrophage cytotoxicity Lais Alonso, Laís Flávia Nunes Lemes, George E Magoulas, Brenda de Lucena Costa, Rodrigo Saar Gomes, Miriam Leandro Dorta, Maria Laura Bolognesi, Luiz Antonio Soares Romeiro, Theodora Calogeropoulou, Antonio Alonso DOI: 10.1590/0074-02760240219

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Anti-PGL-I seropositivity and development of leprosy in contacts: a comprehensive analysis of sociodemographic determinants, genetic susceptibility, and exposure characteristics to Mycobacterium leprae Eyleen Nabyla Alvarenga Niitsuma, Isabela de Caux Bueno, Gabriel da Rocha Fernandes, Mery Natali Silva Abreu, Francisco Carlos Félix Lana DOI: 10.1590/0074-02760240061

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Detection of immunogenic protein components in excretion/secretion products of Acanthamoeba T5 using polyclonal antibodies Lissette Retana-Moreira, Elizabeth Abrahams-Sandí, Marco Ruiz-Campos, Johan Alvarado-Ocampo, Julián Castro, Jacob Lorenzo-Morales, Giovanni Sáenz-Arce, Antonio Osuna DOI: 10.1590/0074-02760240190

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Assessing the spatial influence of deforestation on malaria incidence in Pará State, Amazon region, Brazil, 2008-2019 Carla Gisele Ribeiro Garcia, Beatriz C Ribeiro, Alcinês S Souza Júnior, Lilian Jéssica P Lima, Marinete M Póvoa, Gabriel Z Laporta, Maristela G Cunha DOI: 10.1590/0074-02760240143

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Genome characterisation of the first isolate of human enterovirus c99 from an acute flaccid paralysis case in Brazil Jéssica Tatiane Sauthier, Jéssica Barreto Dias, Cristiane de Sousa Ferreira, Brendo de Oliveira Nascimento Gomes, Ketlyn Araujo Fraga, Elisa Cavalcante Pereira, Bruna Mendonça da Silva, Letícia Ferreira Lima, Irving Martins da Silveira Gonçalves, Audrien Alves Andrade de Souza, Marília Alves Figueira de Melo, Alexandre Araujo Cunha dos Santos, Beatriz de Lima Alessio Müller, Aline dos Santos Moreira, Paola Cristina Resende, Eduardo de Mello Volotão, Edson Elias da Silva DOI: 10.1590/0074-02760240230

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Prevalence of pfhrp2/pfhrp3 gene deletions among patients with Plasmodium falciparum malaria with false-negative in the HRP2-based rapid diagnostic test in Colombia Mario Javier Olivera, Angela Patricia Guerra, Liliana Jazmín Cortés, Aravy Geohanna Suárez-Jurado, María de la Paz Ade, Iván Mauricio Cárdenas DOI: 10.1590/0074-02760240134

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A multicentre comparative study of serological methods for diagnosing Chagas disease in Brazil Alejandro Luquetti Ostermayer, Fernanda Alvarenga Cardoso Medeiros, Jacqueline Araújo Domingos Iturra, Job Alves de Souza Filho, Leonardo Maia Leony, Larissa de Carvalho Medrado Vasconcelos, Liliane da Rocha Siriano, Suelene Brito do Nascimento Tavares, Vinícius Silva Belo, Andréa Silvestre de Sousa, Fred Luciano Neves Santos DOI: 10.1590/0074-02760240282

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X-linked polymorphisms in TLR7 and TLR8 genes are associated with protection against Chikungunya fever Wilker Jose Perez Gotay, Mariella Sousa Coêlho Maciel, Raphael de Oliveira Rodrigues, Cynthia Chester Cardoso, Caroline Nobre Oliveira, Artur Fontenelle Lima Montenegro, Juliana Navarro Ueda Yaochite DOI: 10.1590/0074-02760230224

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A 20-month longitudinal study to evaluate humoral and cellular immunity after COVID-19 vaccines Wlademir Braga Salgado Sobrinho, Bárbara Batista Salgado, Aguyda Rayany Cavalcante Barbosa, Vanessa Araújo Passos, Lisvane Paes Vieira, Lhorruama Dias do Nascimento, Jaila Dias Borges Lalwani, Pritesh Jaychand Lalwani, Paulo Afonso Nogueira DOI: 10.1590/0074-02760240193

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Identification of polymorphisms associated with attenuation of Vif and Vpr in HIV-1 Elite Controllers Suwellen Sardinha Dias de Azevedo, Fernanda Heloise Côrtes, Mariza G Morgado, Brenda Hoagland, Larissa M Villela, Beatriz Grinsztejn, Valdilea Gonçalvez Veloso, Gonzalo Bello DOI: 10.1590/0074-02760240274

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Neurobasal medium enhances titan cell formation in Cryptococcus spp. Juliana Godoy, Igor Avellar-Moura, Juliana Soares, Bruno Pontes, Susana Frases DOI: 10.1590/0074-02760240286

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Trichophyton rubrum inhibits Candida albicans filamentation and its gene expression when grown in biofilms in vitro Níura Madalena Bila, Carolina Orlando Vaso, Jenyffie Araújo Belizário, Mariana M Santoni Biasioli, Ana Marisa Fusco-Almeida, Luis R Martinez, Caroline Barcelos Costa-Orlandi, Maria José Soares Mendes-Giannini DOI: 10.1590/0074-02760240221

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Expanded range of Haemagogus leucocelaenus in yellow fever hotspots: new findings from Santa Catarina State, southern Brazil Sabrina Fernandes Cardoso, Iara Carolini Pinheiro, Larissa Akemi Oliveira Kikuti, Andre Akira Gonzaga Yoshikawa, André Nóbrega Pitaluga, Luísa Damazio Rona Pitaluga DOI: 10.1590/0074-02760240240

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Orthoflavivirus nilense surveillance in the State of Piauí, northeastern Brazil Osmaikon Lisboa Lobato, Tayná da Silva Nogueira, Tobias Emílio Tavares Lima, Felipe José da Costa Andrade, Marília Gabryelle Guimarães de Macedo, Rayane de Souza Pereira, Joilson Xavier, Mariene Ribeiro Amorim, Priscilla Paschoal Barbosa, Alex Sobrinho da Rocha, Silvokleio da Costa Silva, Luiz Carlos Junior Alcantara, William M de Souza, José Luiz Proenca-Modena, Érica Azevedo Costa, Adelino Soares Lima Neto, Lauro César Soares Feitosa, Maria do Socorro Pires e Cruz, Silvana Maria Medeiros de Sousa Silva, Silvia de Araújo França Baêta, Marcelo Adriano da Cunha e Silva Vieira, Sharon L Deem, Lilian Silva Catenacci DOI: 10.1590/0074-02760240218

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Population structure of Anopheles (Kerteszia) bellator in the Brazilian Atlantic Forest Iara Carolini Pinheiro, Kamila Voges, Andre Akira Gonzaga Yoshikawa, Sabrina Fernandes Cardoso, Antonio Bernardo Carvalho, André Nóbrega Pitaluga, Luísa Damazio Pitaluga Rona DOI: 10.1590/0074-02760240287

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Susceptibility of Aedes aegypti to spinosad larvicide and space spray adulticides in Brazil Luciana dos Santos Dias, Ademir Jesus Martins, Cynara de Melo Rodovalho, Diogo Fernandes Bellinato, Tatiana Mingote Ferreira de Ázara, Aline Machado Rapello do Nascimento, Vincent Corbel, Maria de Lourdes da Graça Macoris, Maria Teresa Macoris Andrighetti, José Bento Pereira Lima DOI: 10.1590/0074-02760240270

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Diagnosis of Trypanosoma cruzi infection in Mexican populations: current conventional serology lacks adequate sensitivity and specificity Janine M Ramsey, Keynes de la Cruz-Felix, Ezequiel Tun-Ku, Alejandro G Schijman, Sleidher Gutiérrez, Margarita Virgen-Cuevas, Monica Reyes-Romero, Kenia Escobedo-López, Gilberto Sánchez-González, Angélica Pech-May DOI: 10.1590/0074-02760240224

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In vitro and in vivo studies on the activity and selectivity of butoconazole in experimental infection by Trypanosoma cruzi Gabriela Rodrigues Leite, Denise da Gama Jaen Batista, Marcos Meuser Batista, Krislayne Nunes da Costa, Tomás Mac Loughlin, Emilia M Barrionuevo, Alan Talevi, Lucas N Aberca, Otacilio C Moreira, Amanda Faier-Pereira, Beatriz Iandra da Silva Ferreira, Maria de Nazaré Correia Soeiro DOI: 10.1590/0074-02760240234

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Phospholipids and phospholipase A1 as antigens during the course of experimental Trypanosoma cruzi infection Emanuel Bott, Sebastián Andrés López, Guadalupe Gimenez, María Elisa Solana, María Laura Belaunzarán DOI: 10.1590/0074-02760240281

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Infection of endothelial cells by Streptococcus agalactiae reveals potential role of PI-2b pilus on endothelial barrier dysfunction Jessica Silva Santos de Oliveira, Bruna Alves da Silva Pimentel, Leonardo Nagao Ferreira, Maria Eduarda Negreiro e Silva, Gabriela da Silva Santos, Prescilla Emy Nagao DOI: 10.1590/0074-02760250077

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Concomitant use of anti-leishmanial therapy and antibacterial prophylaxis reduces plasma LPS levels and improves several aspects of experimental Leishmania infantum infection in golden hamsters Joanna Reis Santos-Oliveira, Maria Luciana Silva-Freitas, Marcelle da Senhora Cappato, Elaine Marques-Paulo, Milla Bezerra Paiva, Sandra Regina Soares, Dayane Alvarinho de Oliveira, Eduardo José Lopes-Torres, Marcelo Pelajo-Machado, Eduardo Fonseca Pinto, Jose Angelo L Lindoso, Hiro Goto, Alda M Da-Cruz DOI: 10.1590/0074-02760240266

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The impact of probiotic administration in vivo on peritoneal mouse macrophages infected by Leishmania amazonensis ex vivo Lauren Van den Broeck, Raquel Silva de Azevedo, Ludmila Ferreira de Almeida Fiuza, Marcos Meuser Batista, Cynthia Machado Cascabulho, Ewout Van de Velde, Serge Van Calenbergh, Guy Caljon, Maria de Nazaré Correia Soeiro DOI: 10.1590/0074-02760250014

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The heat-stable enterotoxin ST gene cassettes in Vibrio cholerae and Vibrio mimicus superintegrons are differentially expressed due to their promoter versions Érica Lourenço da Fonseca, Fernanda dos Santos Freitas, Sérgio Mascarenhas Morgado, Ana Carolina Paulo Vicente DOI: 10.1590/0074-02760240212

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Foodborne acute gastroenteritis outbreak associated with a rare norovirus recombinant GII.10[P16] genotype, Brazil, 2023 Fernanda Marcicano Burlandy, Fábio Correia Malta, Mateus de Souza Mello, Alexandre Madi Fialho, Gabriel Assad Baduy, Ronise Valéria Guarnier, Kely Cristiane Souto Moreira, Tulio Machado Fumian DOI: 10.1590/0074-02760250085

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The impact of probiotic administration on experimental in vitro and in vivo infection by Trypanosoma cruzi Denise da Gama Jaén Batista, Lara Calheiros Missagia, Kelly Cristina Demarque, Gabriel Melo de Oliveira, Marcos Meuser Batista, Maria de Nazaré Correia Soeiro DOI: 10.1590/0074-02760240272

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The activity of miltefosine combined with oral probiotics in a mouse model of cutaneous leishmaniasis Yevva Cranshoff, Raquel Azevedo, Marcos Meuser Batista, Kelly Cristina Demarque, Roberson Donola Girão, Amanda Faier-Pereira, Beatriz Iandra da Silva Ferreira, Otacilio Moreira, Cynthia Machado Cascabulho, Ludmila Ferreira Fiuza, Guy Caljon, Maria de Nazaré Correia Soeiro DOI: 10.1590/0074-02760250056

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IgY antibodies/Cysteamine: simple and effective methodology for electrochemical detection of SARS-CoV-2 S-protein Ariamna Gandarilla, Yonny Romaguera-Barcelay, Juliane Corrêa Glória, Luciana Freire, Taisa Farias, Jessica Feitosa, Carlos Anzola, Luís André Morais Mariuba, Walter Ricardo Brito DOI: 10.1590/0074-02760250074

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Concomitant immunity against superimposed homologous Echinostoma caproni infections in mice is mediated by interleuquin-25 Paola Cociancic, Emma Fiallos, José Guillermo Esteban, Carla Muñoz-Antoli, Rafael Toledo DOI: 10.1590/0074-02760250004

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Patients with Trichinella spiralis infection display unmodified antigen-specific immune response to SARS-CoV-2 Ivana Mitic, Sofija Glamoclija, Natasa Radulovic, Ljiljana Sabljic, Sergej Tomic, Alisa Gruden-Movsesijan, Ljiljana Sofronic-Milosavljevic DOI: 10.1590/0074-02760250044

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Reconstructing Sordida subcomplex (Hemiptera, Reduviidae, Triatominae) phylogeny across species distribution range Gabriela Burgueño-Rodríguez, Julieta Nattero, Néstor Ríos, Romina V Piccinali, Ana L Carbajal-de-la-Fuente, Francisco Panzera, Catarina Macedo Lopes, Patricia A Lobbia, Antonieta Rojas de Arias, Bruno A Sansoni-Ruidíaz, María J Cavallo, Claudia S Rodríguez, Pedro Lorite, María C Vega-Gómez, Miriam Rolon, Sebastián Pita DOI: 10.1590/0074-02760250088

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Breaking the ice − simplified freeze-fracture of parasitic protists: a cost-effective approach without highly specialised equipment Marcia Attias, Luis Otávio da Silva Pacheco, Sharmila Fiama das Neves Ortiz, Raphael Verdan, Kildare Miranda, Ana Paula Gadelha, Wanderley de Souza, Marlene Benchimol DOI: 10.1590/0074-02760250060

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Evidence of ascariasis in a Celtic newborn from northern Italy Ramón López-Gijón, Wolf-Rüdiger Teegen, Zita Laffranchi, Daniele Vitali, Albert Zink, Marco Milella DOI: 10.1590/0074-02760250091

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First isolation of Mycobacterium brisbanense from humans in the Americas Carlos Eduardo Dias Campos, Rachel dos Santos de Sena Vasconcelos, William Marco Vicente da Silva, Luciana Distásio de Carvalho, Melissa de Almeida Barbosa Eccard, Isabelle Pinheiro Nobre dos Santos, Jesus Pais Ramos DOI: 10.1590/0074-02760250063

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Influence of a hyperglycaemic diet on Trypanosoma cruzi infection in mice model Aline Coelho das Mercês¹, Flávia de Souza Marques, Bruno Teixeira Martins, Gabriel José Lucas Moreira, Bruno Mendes Roatt, Cláudia Martins Carneiro, Silvia de Paula Gomes, Joana Ferreira do Amaral, Paula Melo de Abreu Vieira DOI: 10.1590/0074-02760250092

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Mosquito-disseminated diflubenzuron and spinosad as alternatives to mosquito-disseminated pyriproxyfen: a proof-of-concept, blind, controlled comparison in experimental cages Gabriela Brandina Aquino de Abreu, Ayrton Sena Gouveia, Francisco Augusto da Silva Ferreira, José Joaquín Carvajal-Cortés, Cláudia Torres Codeço, Fernando Abad-Franch, Sérgio Luiz Bessa Luz DOI: 10.1590/0074-02760250160

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Sex influences murine T cell responses to vaccination with BCG or BCG∆BCG1419 grown as biofilms   Mario Alberto Flores-Valdez, Cristian Alfredo Segura-Cerda, César Pedroza-Roldán, Jorge Gómez-Haro, Dulce Mata-Espinosa, María Guadalupe Jorge-Espinoza DOI: 10.1590/0074-02760250015

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Viral metagenomics in mosquitoes as potential vectors of arboviruses in the Colombian Caribbean: characterization of a “core” regional RNA virome Richard Hoyos-López, Daniel Echeverri-De la Hoz, Caty Martínez-Bravo, Bertha Gastelbondo-Pastrana, Maira Alemán-Santos, Evelin Garay, Yesica López, Héctor Contreras, Ketty Galeano, German Arrieta, Salim Mattar DOI: 10.1590/0074-027602500131

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Entomo-virological investigation in urban forest fragments and intradomiciles during a dengue outbreak in Salinas, MG, Brazil Cirilo Henrique de Oliveira, Thaynara de Jesus Teixeira, Rudá Mahayana Cordeiro de Barros, Arlei Bispo de Araújo, Aline Tátila Ferreira, Danielle Costa Capistrano Chaves, Fabrício Souza Campos, Luiz Marcelo Ribeiro Tomé, Natalia Rocha Guimarães, Talita Émile Ribeiro Adelino, Felipe Campos de Melo Iani, Luiz Carlos Júnior Alcantara, Walter Santos de Araújo, Filipe Vieira Santos de Abreu DOI: 10.1590/0074-02760250086

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Trypanosomatid research in Brazil: a systematic analysis of regional and temporal trends Bárbara Marinho, Izabela Mamede, Júlia Raspante Martins, André Rodrigues, Ana Gabrielle Batista de Melo, Adalberto Sales Miranda-Junior, Alice Rios Neto, Amanda Carolina da Silva Nunes, Bruno Carvalho Resende, Dáfne Oliveira, Darlan Oliveira da Silva, Frederico Gabriel de Carvalho Oliveira, Jéssica Duarte, Lorrane Diniz de Carvalho Silva, Wesley Roger Rodrigues Ferreira, Daniela De Laet-Souza, Andrea Mara Macedo, Glória Regina Franco, Carlos Renato Machado DOI: 10.1590/0074-02760250098

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A comparison of the cost-effectiveness of the current standard of care and of the haematology analyser XN31-microscopy combination for diagnosing malaria in a nonendemic country Stephane Picot, Anne-Lise Bienvenu DOI: 10.1590/0074-02760250078

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Extracellular vesicles isolated from the plasma of COVID-19 and sepsis patients: characterisation and association with clinical outcomes Jaques Franco Novaes de Carvalho, Paula Meneghetti, Gabriela Rodrigues Barbosa, Marina Malheiros Araújo Silvestrini, Sidneia Sousa Santos, Flávio Geraldo Freitas, Daniela Boschetti, Nancy Cristina Junqueira Bellei, Andréa Teixeira de Carvalho, Ana Claudia Torrecilhas, Reinaldo Salomao DOI: 10.1590/0074-02760250109

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Behavioural responses of Anopheles darlingi (Diptera: Culicidae) to host odours: insights from vertical and horizontal olfactometers   Thais Costa dos Santos, Moreno Magalhães De Souza Rodrigues, Elis Paula de Almeida Batista, Kelly da Silva Paixão, Álvaro Eduardo Eiras, Gabriel Zorello Laporta, Alexandre de Almeida e Silva DOI: 10.1590/0074-02760250154

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Holocene man-occupied caves and transformed wetlands as facilitating factors for Leishmania infantum in South America Sérvio Pontes Ribeiro, Camila de Paula Dias, Rafael Vieira Duarte, Maria Fernanda Brito de Almeida, Luccas Gabriel Ferreira Malta, José Dilermando Andrade Filho, Alexandre Barbosa Reis, Marcos Horácio Pereira, Carlos EV Grelle, Jesus G Valenzuela, Tiago Donatelli Serafim, Nelder Figueredo Gontijo DOI: 10.1590/0074-02760250190

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Global silent transmission of the class A β-lactamase LAP-2 by plasmid transfer and clonal expansion of Klebsiella pneumoniae lineages Nathália Maria Santiago Bighi, Sérgio Mascarenhas Morgado, Fernanda dos Santos Freitas, Ana Carolina Paulo Vicente, Érica Lourenço da Fonseca DOI: 10.1590/0074-02760250120

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Therapeutic potential of hookworm proteins in promoting regulatory immune responses to modulate Trypanosoma cruzi induced liver inflammation and oxidative stress Maria Jose Villar, Cristina Poveda, Bin Zhan, Maya Gonsoulin, Kathryn M Jones DOI: 10.1590/0074-02760250123

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First report of canine Chagas disease on the Caribbean Island of Trinidad Rod Suepaul, Azad Mohammed, Nicole L Gottdenker, Indira Pargass, Christopher Oura, Adesh Ramsubhag, Lana Gyan, Vrijesh Tripathi, Jennifer K Peterson DOI: 10.1590/0074-02760250199

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Detection of Trypanosoma cruzi-infected triatomines in Iquitos: possible incipient colonisation in the largest metropolis of the Peruvian Amazon Fabiola Díaz-Soria, Karine Zevallos, Bryan Cabrera-Campos, Carmen Sinti-Hesse, Sebastià Jaume-Ramis, Wieslawa Alava-Flores, Darcy Acho-Bernuy, Silvia Vega-Chirinos, Jesús Pinto-Caballero, César Ramal-Asayag, Moisés Sihuincha, Claudia Paredes-Esquivel DOI: 10.1590/0074-02760240257

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Mitochondrial genomes and phylogeny of Atratus and Educator Group species of the Melanoconion Section of Culex (Melanoconion) (Diptera: Culicidae) Tatiane MP Oliveira , Peter G Foster, Ivy LR Sá, Maria Anice M Sallum DOI: 10.1590/0074-02760250125

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LC3-associated phagocytosis in macrophage responses to Paracoccidioides spp. Getúlio Pereira de Oliveira Júnior, Herdson Renney de Sousa, Kaio César de Melo Gorgonha, Lara Laís Montalvão Tomaz, Tatiana Karla dos Santos Borges, Kellyanne Teixeira Rangel, Scott Fabricant, Fernanda Koser Gustafson, Lucas Friaça Albuquerque, Angelo Rossi Neto, Fabián Andrés Hurtado, Hugo Costa Paes, Arturo Casadevall, Ildinete Silva-Pereira, Maria Sueli Soares Felipe, Patrícia Albuquerque, André Moraes Nicola DOI: 10.1590/0074-02760250089

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Evaluation of the insecticide custody chain and its relationship with malaria burden in the Brazilian Amazon: a process and exploratory impact assessment (2019-2023) Marcela Lima Dourado, Rafaella Albuquerque e Silva Márcia Caldas de Castro, Cássio Roberto Leonel Peterka, Carolina Ribas Kluge, Daniele Castro, José Bento Pereira Lima DOI: 10.1590/0074-02760250152

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Schistosoma mansoni soluble egg antigen and its key proteins differentially affect dextran sodium sulphate-induced inflammatory bowel disease Hsiang-Wei Fan, Ho Yin Pekkle Lam DOI: 10.1590/0074-02760250243

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Entomo-virological investigation during the epizootic outbreak of sylvatic yellow fever in Rio Grande do Sul, Brazil, between 2021 and 2022 Nícolas Felipe Drumm Müller, Marcelo de Moura Lima Edmilson dos Santos, Aline Alves Scarpellini Campos, Thomas Rosa Menegazzi, Alanis Silva Melgarejo, Bruna Paredes-Galarza, Lina Violet-Lozano, Martha Trindade Oliveira, Cirilo Henrique Oliveira, Paulo Michel Roehe, Fabrício Souza Campos, Filipe Vieira Santos de Abreu, Jáder da Cruz Cardoso, Ana Cláudia Franco DOI: 10.1590/0074-02760250169

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Comprehensive identification and co-expression analysis of long non-coding RNAs across eight timepoints of Schistosoma mansoni life cycle Flávia Arêdes-Rocha, Cristian Chaparro, Christoph Grunau, Renata Guerra-Sá DOI: 10.1590/0074-02760250114

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Miracidia as main source for autofluorescence of Schistosoma mansoni eggs Danielle Segóvia Chrysóstomo de Almeida Pereira, Laila Oliveira Vaz Oliveira, Felipe Tonon Firmino, Thomas Hanscheid, Rock Pulak, Malcolm Jones, Silvio Dolabella, Deborah Negrão-Corrêa, Carlos Graeff-Teixeira DOI: 10.1590/0074-02760250215

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Molecular Characterization of Trypanosoma cruzi in Triatoma dimidiata from a Highland Locality in Western Panama ACCEPTED ARTICLES / PRELIMINARY VERSION V Pineda, K González, JE Calzada, A Saldaña DOI: 10.1590/0074-02760250172

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Transcriptomic dynamics reveals sequential acquisition of complement resistance during prolonged starvation of Trypanosoma cruzi epimastigote Leticia Pérez-Díaz, Pablo Smircich, Fabricio Hernandez, Martin Ciganda, Ma Ana Duhagon, Beatriz Garat DOI: 10.1590/0074-02760250127

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Transcriptomics of Plasmodium vivax rosetting ACCEPTED ARTICLES / PRELIMINARY VERSION Catarina Bourgard, Julia W Ferraboli, Stefanie CP Lopes, Marcus V G Lacerda, Per Sunnerhagen, Letusa Albrecht, Fabio TM Costa DOI: 10.1590/0074-02760250198

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Immune dysregulation, apoptosis impairment, and enhanced seroreactivity to Anisakis simplex in Crohn’s disease: interplay of IL-7/IL-7R signalling and CD132 deficiency Carmen Cuéllar, Carolina Hurtado-Marcos, Elizabeth Valdivieso, Lucianna Vaccaro, Juan González-Fernández, Ana Isabel Jiménez, Jaume Pérez-Griera, Salvador Benlloch, Cirilo Amorós, Rafael Gil-Borrás, Rosa Sorando-Serra, María José Cano-Cano, Juan Carlos Andreu-Ballester DOI: 10.1590/0074-02760250129

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Genome mining and characterization of biosynthetic clusters in Aspergillus japonicus isolated from the Amazon rainforest ACCEPTED ARTICLES / PRELIMINARY VERSION Josy C Rodrigues, Maria Eduarda Grisolia, Alice da Silva Queiroz, Ana L Rodrigues Lima, Clarice VS Goiabeira, Leila de Mendonça Lima, Ormezinda CC Fernandes DOI: 10.1590/0074-02760250075

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Differential expression of miRNAs in vero cells after mayaro virus infection ACCEPTED ARTICLES / PRELIMINARY VERSION Juliana Santana de Curcio, Lívia do Carmo Silva, Evandro Novaes, Elisângela de Paula Silveira-Lacerda DOI: 10.1590/0074-02760250177

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On the 125th anniversary of the Oswaldo Cruz Institute, the postgraduate program in tropical medicine celebrates 45 years of achievements in an evolving landscape ACCEPTED ARTICLES / PRELIMINARY VERSION Livia Agualuza Mangeon, Martha Cecilia Suarez-Mutis, Alda Maria Da-Cruz, Elba Regina Sampaio de Lemos, Livia Melo Villar, Marco Aurelio Pereira Horta, Márcio Neves Bóia, Vanessa Salete De Paula, Filipe Anibal Carvalho-Costa DOI: 10.1590/0074-02760250313

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The causes of covid-19: na uncontrolled experiment in evolution, causation, and public health ACCEPTED ARTICLES / PRELIMINARY VERSION Ricardo Waizbort DOI: 10.1590/0074-02760250285

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Impact of the COVID-19 pandemic on mortality among patients with TB–HIV coinfection in the Brazilian Amazon: a case–control study ACCEPTED ARTICLES / PRELIMINARY VERSION Lucilaide Oliveira Santos, Filipe Anibal Carvalho-Costa, Maria Graciede Filha Santarém Andrade, Maria do Socorro Guimarães de Souza, Nestor Cordeiro dos Santos Neto, Valdete Santos de Araújo, Flor Ernestina Martinez Espinosa, Martha Cecilia Suarez-Mutis DOI: 10.1590/0074-02760250321

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Deferred blood donors in the state of Roraima, Brazilian Amazon: reasons for unsuitability and seroprevalence of transfusion-transmitted pathogens ACCEPTED ARTICLES / PRELIMINARY VERSION Daniela Ribeiro Roque, Fabiana Granja, Filipe Anibal Carvalho-Costa DOI: 10.1590/0074-02760250320

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Cladistics of South American Triatoma (Hemiptera: Reduviidae): a morphological overview of the Triatoma infestans complex ACCEPTED ARTICLES / PRELIMINARY VERSION João Paulo Sales Oliveira-Correia, Hélcio Reinaldo Gil-Santana, Cleber Galvão DOI: 10.1590/0074-02760250293

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Wolbachia introgression in Rio de Janeiro remains at sub-optimal levels 30 months after its crash: challenges in the sustainability of wMel interventions for dengue control   ACCEPTED ARTICLES / PRELIMINARY VERSION Karine Pedreira Padilha, Gabriela Azambuja Garcia, Rayane Teles-de-Freitas, Franck Jeannot Gnonhoue, Mariana Rocha David, Jessica Corrêa-Antônio, Felipe de Oliveira, Luiz Paulo Brito, Luciana Dias, Ademir Jesus Martins, Vincent Corbel, José Bento Pereira Lima, Gabriel Luz Wallau, Ary Hoffmann, Oswaldo Gonçalves Cruz, Daniel Antunes Maciel Villela, Márcio Galvão Pavan, Rafael Maciel-de-Freitas DOI: 10.1590/0074-02760250212

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Production of digital social technologies to promote health and digital citizenship with high school students ACCEPTED ARTICLES / PRELIMINARY VERSION Roberto Todor, Mariana Alberti Gonçalves, Tania Cremonini Araújo-Jorge, Luciana Ribeiro Garzoni DOI: 10.1590/0074-02760250331

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Inside the blood with ArtScience at Chagas Express XXI: innovation for science education and health promotion ACCEPTED ARTICLES / PRELIMINARY VERSION Taiana Oliveira, Luciana Garzoni, Thallyta Vieira, Rita Machado, Roberto Ferreira, Tania Araujo-Jorge DOI: 10.1590/0074-02760250319

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Investigation of neurotropic arboviroses in wild and domestic animals in amazon region, 2023-2024 ACCEPTED ARTICLES / PRELIMINARY VERSION Daniel Jun Hayashi, Bruno Tardelli Diniz Nunes, Sandro Patroca da Silva, Tânia Cristina Alves da Silveira da Cunha, Francisco Amilton dos Santos Paiva, Ivy TsuyaEssashika Prazeres, Alessandra da Conceição Miranda Santos, Landeson Junior Leopoldino Barros, Ana Cláudia da Silva Ribeiro, Felipe Baraldi Sobral, Luiz Mário Fernandes, Taciana Fernandes Souza Barbosa Coelho, Valéria Lima Carvalho, Ana Cecilia Ribeiro Cruz, Daniele Barbosa de Almeida Medeiros, Livia Medeiros Neves Casseb DOI: 10.1590/0074-02760250013

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Effects of exposure to Rickettsia bellii on reservoir competence of guinea pigs for Rickettsia rickettsii ACCEPTED ARTICLES / PRELIMINARY VERSION Lina C Binder, Carlos Eduardo C Fanchini, Herbert S Soares, Talita BS dos Santos, Sueli A Taniwaki, Marcelly B Nassar, Andrea C Fogaça, Maria Carolina A Serpa, Matheus P Martins, Marcelo B Labruna DOI: 10.1590/0074-02760250195

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Reframing vector control: land use and climate shape malaria risk in Amazonian communities ACCEPTED ARTICLES / PRELIMINARY VERSION André Luis Acosta, Eduardo Sterlino Bergo, Elder Augusto G Figueira, Jan E Conn, Maria Anice Mureb Sallum DOI: 10.1590/0074-02760250171

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