Editorial

Memórias do Instituto Oswaldo Cruz celebrates 115 years of scientific publishing: what it needs to keep moving on… Adeilton Alves Brandão, Ana Carolina P Vicente DOI: 10.1590/0074-02760240003

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Reviews

Worldwide distribution, symptoms and diagnosis of the coinfections between malaria and arboviral diseases: a systematic review Marcelo Cerilo-Filho, Marcelo de L Arouca, Estela dos S Medeiros, Myrela CS de Jesus, Marrara P Sampaio, Nathália F Reis, José RS Silva, Andréa RS Baptista, Luciane M Storti-Melo, Ricardo LD Machado DOI: 10.1590/0074-02760240015

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Endocytosis in anaerobic parasitic protists Marlene Benchimol, Wanderley de Souza DOI: 10.1590/0074-02760240058

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You are what you eat: a systematic review exploring the interaction between Brazilian sand flies and their vertebrate food sources Felipe Dutra-Rêgo, Michelli Santos da Silva, Ana Paula Isnard, Jansen Fernandes Medeiros, José Dilermando Andrade Filho, Mariana Lourenço Freire DOI: 10.1590/0074-02760240055

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Overview of extracellular vesicles in pathogens with special focus on human extracellular protozoan parasites Johan Alvarado-Ocampo, Elizabeth Abrahams-Sandí, Lissette Retana-Moreira DOI: 10.1590/0074-02760240073

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Perspectives

The present and future research agenda of sporotrichosis on the silver anniversary of zoonotic sporotrichosis in Rio de Janeiro, Brazil Rodrigo Almeida-Paes, Antonio Carlos Francesconi do Valle, Dayvison Francis Saraiva Freitas, Priscila Marques de Macedo, Rosely Maria Zancopé-Oliveira, Maria Clara Gutierrez-Galhardo DOI: 10.1590/0074-02760230208

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Drug screening and development cascade for Chagas disease: an update of in vitro and in vivo experimental models Maria de Nazaré Correia Soeiro, Policarpo Ademar Sales-Junior, Valeria Rêgo Alves Pereira, Marcos André Vannier-Santos, Silvane Maria Fonseca Murta, Andrea Silvestre de Sousa, Luiz Henrique Conde Sangenis, Alejandro Marcel Hasslocher-Moreno, Núbia Boechat, Frederico Silva Castelo Branco, Fabíola Barbieri Holetz, Andrea Rodrigues Ávila, Mirian Claudia de Souza Pereira DOI: 10.1590/0074-02760240057

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Advances in the development of new vaccines for tuberculosis and Brazil's role in the effort forward the End TB strategy ACCEPTED ARTICLES / PRELIMINARY VERSION Ana Paula Junqueira-Kipnis, Luciana Cerqueira Cesar Leite, Júlio Croda, Erica Chimara, Anna Cristina C Carvalho, Ricard Alexandre Arcêncio DOI: 10.1590/0074-02760240093

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Epoxy-α-lapachone in nanosystem: a prototype drug for leishmaniasis assessed in the binomial BALB/c - Leishmania (Leishmania) amazonensis ACCEPTED ARTICLES / PRELIMINARY VERSION Juliana Figueiredo Peixoto, Luiz Filipe Gonçalves-Oliveira, Geovane Dias-Lopes, Franklin Souza-Silva, Carlos Roberto Alves DOI: 10.1590/0074-02760240115

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Research Articles

The absence of eosinophils is associated with early metastatic lesions in Leishmania amazonensis-infected mice Gregório Guilherme Almeida, Tassiane Assíria Martins Luehring, Pierre Henrique de Menezes Paixão, Rodrigo Pedro Soares, André Luís Branco de Barros, Rubens Lima do Monte-Neto, Wagner Luiz Tafuri, Deborah Aparecida Negrão-Corrêa, Ricardo Gonçalves DOI: 10.1590/0074-02760220242

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Leishmania (Leishmania) infantum DNA detection in Nyssomyia neivai in Vale do Ribeira, Paraná, Brazil Letícia Cristina Morelli, Daniela de Pita-Pereira, Constança Britto, Thais de Araújo-Pereira, Lucas Alexandre Farias de Souza, Kelly de Oliveira Germano, Andrey José de Andrade, Magda Clara Vieira da Costa-Ribeiro DOI: 10.1590/0074-02760230173

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Characterisation of an area of coexistent visceral and cutaneous leishmaniasis transmission in the State of Piauí, Brazil Silvia Alcântara Vasconcelos, Raimundo Leoberto Torres de Sousa, Enéas Costa Junior, João Paulo Diniz e Souza, Diane Cavalcante, Antônio Carlos Lima da Silva, Ivete Lopes de Mendonça, Jacenir Mallet6, Clarissa Romero Teixeira, Guilherme Loureiro Werneck, Thais Araújo-Pereira, Daniela Pita-Pereira, Constança Britto, Maurício Luiz Vilela, Regis Gomes DOI: 10.1590/0074-02760230181

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Different profiles of chemokines, cytokines and cell growth factors in plasma samples from patients with leprosy, leprosy reactions and households contacts Jairo Campos de Carvalho, Marcelo Antônio Pascoal-Xavier, Marcelo Grossi Araújo, Andrea Teixeira-Carvalho, Olindo Assis Martins-Filho, Vanessa Peruhype-Magalhães, Jordana Grazziela Alves Coelho-dos-Reis, Márcio Sobreira Silva Araújo DOI: 10.1590/0074-02760230129

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Simple and promising paper-based electrochemical platform for serological detection of American tegumentary leishmaniasis Daniela E Barraza, Paula I Nanni, María E Bracamonte, Roberto E Chaile, Carla B Goy, Leonardo Acuña, Jorge D Marco, Rossana E Madrid DOI: 10.1590/0074-02760230149

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FVB/NJ strain as a mouse model for cutaneous leishmaniasis by Leishmania (L.) amazonensis Guilherme Moreira Paiva Carrara, Beatriz Simonsen Stolf DOI: 10.1590/0074-02760230182

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In silico identification of drug targets and vaccine candidates against Bartonella quintana: a subtractive proteomics approach Shabir Ahmad, Hugo Verli DOI: 10.1590/0074-02760230040

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Characterisation of the merozoite thrombospondin related anonymous protein (MTRAP) of Plasmodium berghei as a transmission-blocking antigen Xiomara Alexandra Gaitán, Juliana Calit, Irina Dobrescu, Marisé Solórzano Ramos, Alba Marina Gimenez, Daniel Youssef Bargieri DOI: 10.1590/0074-02760230217

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Leishmania (Sauroleishmania) tarentolae versus pathogenic species: comparative evaluation of protease activity, glycoconjugates, resistance to complement and metabolome composition Filipe Fideles Duarte Andrade, Jéssica Gardone Vitório, Gisele André Baptista Canuto, Fernanda Freire Campos Nunes, Isabela Aurora Rodrigues, Ana Paula Martins Morais Almeida, Frederico Crepaldi Nascimento, Adriana Oliveira Costa, Tamara da Silva Vieira, Ana Carolina Carvalho Silva, Leiliane Coelho André, Célia Maria Ferreira Gontijo, Caroline Junqueira, Juliano Simões de Toledo, Ana Paula Fernandes, Rodrigo Pedro Soares DOI: 10.1590/0074-02760230243

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Improving in vitro screening compounds anti-Trypanosoma cruzi by GFP-expressing parasites Cleyson Mathias Morais Delvoss, Alexandre Haruo Inoue, Rosiane Valeriano da Silva, Stênio Perdigão Fragoso3, Iriane Eger DOI: 10.1590/0074-02760230223

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First case of Oropouche fever detected in the international border region of the Colombian Amazon: clinical characteristics and molecular diagnosis Juan Camilo Grisales-Nieto, Sérgio Luiz Bessa Luz, Valdinete Alves do Nascimento, Felipe Gomes Naveca, Luz Mila Murcia-Montaño, Kelly Natalia Romero-Vesga, Olga Eshter Bellido-Cuellar, José Joaquín Carvajal-Cortés DOI: 10.1590/0074-02760230221

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Innate immune receptors are differentially expressed in mice during experimental Schistosoma mansoni early infection Janete Cunha Lima, Ramayana Morais de Medeiros Brito, Luanderson Cardoso Pereira, Nathalie de Sena Pereira, Manuela Sales Lima Nascimento, Alan Lane de Melo, Paulo Marcos Matta Guedes DOI: 10.1590/0074-02760240013

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The risk of vector transmission of Trypanosoma cruzi remains high in the State of Paraná João Vitor S Trovo, Michele Martha Weber-Lima, Bianca Prado-Costa, Giullia F Iunklaus, Andrey J Andrade, Thadeu Sobral-Souza, Renata L Muylaert, Larissa M Alvarenga, Max Jean O Toledo DOI: 10.1590/0074-02760230226

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Cytopathic effects in Mimivirus infection: understanding the kinetics of virus-cell interaction Gabriel Henrique Pereira Nunes, Juliana dos Santos Oliveira, Victor Alejandro Essus, Allan J Guimarães, Bruno Pontes, Juliana Reis Cortines DOI: 10.1590/0074-02760230186

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Isolation and characterisation of Leishmania (Leishmania) infantum from cutaneous leishmaniasis patients in northeast Brazil Gustavo Henrique Corrêa Soares, Gustavo Rolim Barbosa, Ana Jessica Sousa Coelho, Giovanna Bedin Caetano, Conceição de Maria Pedrozo e Silva de Azevedo, Adriano Cappellazzo Coelho, Mayara Ingrid Souza Lima, Beatriz Simonsen Stolf DOI: 10.1590/0074-02760240026

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Assessing proteases and enzymes of the trypanothione system in subpopulations of Leishmania (Viannia) braziliensis Thor strain during macrophage infection Barbara Cristina de Albuquerque-Melo, Bernardo Acácio Santini Pereira, Vítor Ennes-Vidal, Maria Eduarda Pinto Gonçalves, Luzia Monteiro de Castro Côrtes, Léa Cysne-Finkelstein, Herbert Leonel de Matos Guedes, Geovane Dias-Lopes, Carlos Roberto Alves DOI: 10.1590/0074-02760240038

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Irrigation, migration and infestation: a case study of Chagas disease vectors and bed bugs in El Pedregal, Peru Raquel Gonçalves, Kathryn P Hacker, Carlos Condori, Sherrie Xie, Katty Borrini-Mayori, Lina Mollesaca Riveros, Roger Quispe Apaza, Manuel Ysidro Arratea, Gustavo Nativio, Ricardo Castillo-Neyra, Valerie A Paz-Soldan, Michael Z Levy DOI: 10.1590/0074-02760240002

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Sublingual microcirculatory alterations in Chagas disease: an observational study in an endemic rural population Jorge Emilio De All, Juan Francisco Caminos Eguillor, Simón Marcelo Cohen, Héctor Freilij, Arnaldo Dubin DOI: 10.1590/0074-02760240018

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Assessment of immune responses to a Comirnaty® booster following CoronaVac® vaccination in healthcare workers Lucas Bochnia-Bueno, Gabriela Mattoso Coelho, Allan Henrique Depieri Cataneo, Camila Zanluca, Laura Holtman Ferreira, Luciano Pamplona de Goes Cavalcanti, Marco Antonio de Freitas Clementino, Juliana Navarro Ueda Yaochite, Hellen Geremias dos Santos, Meri Bordignon Nogueira, Claudia Nunes Duarte dos Santos, Sonia Mara Raboni DOI: 10.1590/0074-02760230239

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Iron and vitamin D intake on a diet are able to modify the in vitro immune response to Mycobacterium leprae Bruna Letícia Martins, Jonatas Perico, Daniele Ferreira de Faria Bertoluci, Adriana Sierra Assencio Almeida Barbosa, Patricia Sammarco Rosa, Maria Renata Sales Nogueira, Vânia Nieto Brito de Souza, Ana Carla Pereira Latini DOI: 10.1590/0074-02760230178

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PPE59 antibodies in tuberculous patients and potential use for diagnosis when assayed with other rapid biomarkers Ana Carla de Paulo Mulinari, Isabela Gama Sardella, Vania Maria C da Silva, Alberto Matteelli, Anna Cristina C Carvalho, Maria Helena Féres Saad DOI: 10.1590/0074-02760230183

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Leishmania spp. genetic factors associated with cutaneous leishmaniasis antimony pentavalent drug resistance: a systematic review Raphaela Lisboa Andrade Nery, Thaline Mabel Sousa Santos, Luana Leandro Gois, Aldina Barral, Ricardo Khouri, Caroline Alves Feitosa, Luciane Amorim Santos DOI: 10.1590/0074-02760230240

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HIV-1 controllers exhibit an enhanced antiretroviral innate state characterised by overexpression of p21 and MCPIP1 and silencing of ERVK-6 RNA expression Suwellen Sardinha Dias de Azevedo, Marcelo Ribeiro-Alves, Fernanda Heloise Côrtes, Edson Delatorre, Brenda Hoagland, Larissa M Villela, Beatriz Grinsztejn, Valdilea Gonçalvez Veloso, Mariza G Morgado, Thiago Moreno L Souza, Gonzalo Bello DOI: 10.1590/0074-02760240071

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Homologous equivalence study of immunogenicity after third dose of Covid-19 vaccine (recombinant) with an interval of six months after the second dose, comparing the interval of eight and 12 weeks between the first two doses Clarice Monteiro Vianna, Gloria Regina da Silva e Sá, Maria Vitória Hadland Seid, Luiz Antonio Bastos Camacho, Janaína Reis Xavier, Vitor Cardoso da Gama, Thalita da Matta de Castro, Ewerton Alves Portela dos Santos, Camila Dias de Almeida, Robson Leite de Souza Cruz, Marilda Siqueira, Maria de Lourdes de Sousa Maia, Clara Lucy de Vasconcellos Ferroco, Mia Ferreira de Araújo, Luis Fernando López Tort, Braulia Costa Caetano DOI: 10.1590/0074-02760240094

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Climate change-induced degradation of expert range maps drawn for kissing bugs (Hemiptera: Reduviidae) and long-standing current and future sampling gaps across the Americas Vaughn Shirey, Jorge Rabinovich DOI: 10.1590/0074-02760230100

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First concrete documentation for presence of Aedes (Stegomyia) albopictus in Bolivia: Dispelling previous anecdotes ACCEPTED ARTICLES / PRELIMINARY VERSION Frédéric Lardeux, Philippe Boussès, Rosenka Tejerina-Lardeux, Audric Berger, Christian Barnabé, Lineth Garcia DOI: 10.1590/0074-02760240063

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Description of the new HIV-1 intersubtype B/C circulating recombinant form (CRF146_BC) detected in Brazil Rodrigo Cunha Oliveira, Darren Martin, Juliana Sacramento Mota de Souza, Luiz Carlos Júnior Alcântara, Monick Lindenmeyer Guimarães, Carlos Brites, Joana Paixão Monteiro-Cunha DOI: 10.1590/0074-02760230214

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Point-of-Care testing for COVID-19: a simple two-step molecular diagnostic development and validation during the SARS-CoV-2 pandemic ACCEPTED ARTICLES / PRELIMINARY VERSION Andre AG Yoshikawa, Sabrina F Cardoso, Lívia B Eslabão, Iara C Pinheiro, Priscila Valverde, Gisele Caminha, Oscar B Romero, Leandro Medeiros, Luísa DP Rona, André N Pitaluga DOI: 10.1590/0074-02760230236

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Rapid on-site detection of Echinococcosis and Schistosomiasis based on RPA ACCEPTED ARTICLES / PRELIMINARY VERSION Lvbo Tian, Ying Shi, Yu Yang, Yuchen Wang DOI: 10.1590/0074-02760230244

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Detached epithelial cell plugs from the upper respiratory tract favour distal lung injury in Golden Syrian hamsters (Mesocricetus auratus) when experimentally infected with the A.2 Brazilian SARS-CoV-2 strain ACCEPTED ARTICLES / PRELIMINARY VERSION Marcelo Pelajo-Machado, Alexandre dos Santos da Silva, Daniela del Rosario Flores Rodrigues, Milla Bezerra Paiva, Rodrigo Muller, Luciana Jesus da Costa, Pedro Paulo Abreu Manso, João Paulo Rodrigues dos Santos, Manuela de Souza Ramalho Ferreira da Silva, Arthur Daniel Rocha Alves, Monica Santos Freitas, Jaqueline Mendes Oliveira, Marcelo Alves Pinto DOI: 10.1590/0074-02760240100

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Characterization of larval habitats of Anopheles (Nyssorhynchus) darlingi and associated species in malaria areas in western Brazilian Amazon ACCEPTED ARTICLES / PRELIMINARY VERSION Fátima dos Santos, Mingrui Xu, Lelys Bravo de Guenni, Ricardo Lourenço-de-Oliveira, Yasmin Rubio-Palis DOI: 10.1590/0074-02760240116

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HSV1-induced enhancement of productive HIV-1 replication is associated with interferon pathway downregulation in human macrophages ACCEPTED ARTICLES / PRELIMINARY VERSION Viviane M Andrade, Filipe S Pereira-Dutra, Juliana L Abrantes, Milene D Miranda, Thiago Moreno L Souza DOI: 10.1590/0074-02760240102

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First comparative genomics analysis of Corynebacterium auriscanis ACCEPTED ARTICLES / PRELIMINARY VERSION Ana Lua de Oliveira Vinhal, Max Roberto Batista Araújo, Evandro Bento Rodrigues, Diogo Luiz de Carvalho Castro, Carine Rodrigues Pereira, Dircéia Aparecida Costa Custódio, Elaine Maria Seles Dorneles, Flávia Figueira Aburjaile, Bertram Brenig, Vasco Azevedo, Marcus Vinicius Canário Viana DOI: 10.1590/0074-02760240156

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