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104 (Suppl.I) July 2009

International symposium on the Centennial of the discovery of Chagas disease

Editorial

Chagas disease centennial anniversary celebration: historical overview and prospective proposals aiming to maintain vector control and improve patient prognosis - a permanent challenge Joseli Lannes-Vieira;Maria de Nazaré Correia Soeiro;Rodrigo Corrêa-Oliveira;Tania Cremonini de Araújo-Jorge PAGE: 5-7 | DOI: 10.1590/S0074-02762009000900003

Foreword

Foreword Ricardo Lourenço de Oliveira;Joseli Lannes-Vieira PAGE: 3 | DOI: 10.1590/S0074-02762009000900002

Original Articles

?-N-acetylglucosamine-linked O-glycans of sialoglycoproteins (Tc-mucins) from Trypanosoma cruzi Colombiana strain Adriane R Todeschini; Eliane G de Almeida; Orlando A Agrellos; Christopher Jones; José O Previato; Lucia Mendonça-Previato PAGE: 270-274 | DOI: 10.1590/S0074-02762009000900035

A century of research: what have we learned about the interaction of Trypanosoma cruzi with host cells? Maria Julia Manso Alves; Renato Arruda Mortara PAGE: 76-88 | DOI: 10.1590/S0074-02762009000900013

All-around care for patients with Chagas disease: a challenge for the XXI century Wilson de Oliveira Jr PAGE: 181-186 | DOI: 10.1590/S0074-02762009000900024

Back to the future in Chagas disease: from animal models to patient cohort studies, progress in immunopathogenesis research Julio Scharfstein ; Juliana de Assis Silva Gomes; Rodrigo Correa-Oliveira PAGE: 187-198 | DOI: 10.1590/S0074-02762009000900025

Biology, diversity and strategies for the monitoring and control of triatomines - Chagas disease vectors Jane Costa ; Marcelo Lorenzo PAGE: 46-51 | DOI: 10.1590/S0074-02762009000900008

Cellular and genetic mechanisms involved in the generation of protective and pathogenic immune responses in human Chagas disease Walderez Ornelas Dutra ; Cristiane Alves Silva Menezes; Fernanda Nobre Amaral Villani; Germano Carneiro da Costa; Alexandre Barcelos Morais da Silveira; Débora d'Ávila Reis; Kenneth J Gollob PAGE: 208-218 | DOI: 10.1590/S0074-02762009000900027

Chagas disease, adipose tissue and the metabolic syndrome Fnu Nagajyothi; Mahalia S Desruisseaux; Louis M Weiss; Streamson Chua; Chris Albanese; Fabiana S Machado; Lisia Esper; Michael P Lisanti; Mauro M Teixeira; Philipp E Scherer; Herbert B Tanowitz PAGE: 219-225 | DOI: 10.1590/S0074-02762009000900028

Chagas heart disease: pathophysiologic mechanisms, prognostic factors and risk stratification Anis Rassi Jr ; Anis Rassi; José Antonio Marin-Neto PAGE: 152-158 | DOI: 10.1590/S0074-02762009000900021

Chronic Trypanosoma cruzi-elicited cardiomyopathy: from the discovery to the proposal of rational therapeutic interventions targeting cell adhesion molecules and chemokine receptors - how to make a dream come true Joseli Lannes-Vieira ; Jaline Coutinho Silverio; Isabela Resende Pereira; Nathália Ferreira Vinagre; Cristiano Marcelo Espinola Carvalho; Cláudia Neto Paiva; Andréa Alice da Silva PAGE: 226-235 | DOI: 10.1590/S0074-02762009000900029

Current epidemiological trends for Chagas disease in Latin America and future challenges in epidemiology, surveillance and health policy Álvaro Moncayo ; Antonio Carlos Silveira PAGE: 17-30 | DOI: 10.1590/S0074-02762009000900005

Current status and perspectives of cell therapy in Chagas disease Milena Botelho Pereira Soares; Ricardo Ribeiro dos Santos PAGE: 325-332 | DOI: 10.1590/S0074-02762009000900043

Diagnosis of Chagas disease: what has been achieved? What remains to be done with regard to diagnosis and follow up studies? Yara M Gomes ; Virginia MB Lorena; Alejandro O Luquetti PAGE: 115-121 | DOI: 10.1590/S0074-02762009000900017

Do Archaea and bacteria co-infection have a role in the pathogenesis of chronic chagasic cardiopathy? Maria de Lourdes Higuchi; Joyce Kawakami; Renata Ikegami; Maysa Beatriz Mandetta Clementino; Flavio M Kawamoto; Marcia M Reis; Edimar Bocchi PAGE: 199-207 | DOI: 10.1590/S0074-02762009000900026

Elimination of Chagas disease transmission: perspectives João Carlos Pinto Dias PAGE: 41-45 | DOI: 10.1590/S0074-02762009000900007

Epidemiology, control and surveillance of Chagas disease - 100 years after its discovery José Rodrigues Coura ; João Carlos Pinto Dias PAGE: 31-40 | DOI: 10.1590/S0074-02762009000900006

Ergosterol biosynthesis and drug development for Chagas disease Julio A Urbina PAGE: 311-318 | DOI: 10.1590/S0074-02762009000900041

Experimental chemotherapy for Chagas disease: 15 years of research contributions from in vivo and in vitro studies Maria de Nazaré C Soeiro; Andréia P Dantas; Anissa Daliry; Cristiane F da Silva; Denise GJ Batista; Elen M de Souza; Gabriel M Oliveira; Kelly Salomão; Marcos Meuser Batista; Michelle GO Pacheco; Patrícia Bernardino da Silva; Ricardo M Santa-Rita; Rubem FS Menna Barreto; David W Boykin; Solange Lisboa de Castro PAGE: 301-310 | DOI: 10.1590/S0074-02762009000900040

Exploiting triatomine behaviour: alternative perspectives for their control Claudio R Lazzari ; Marcelo G Lorenzo PAGE: 65-70 | DOI: 10.1590/S0074-02762009000900011

Immunological and non-immunological effects of cytokines and chemokines in the pathogenesis of chronic Chagas disease cardiomyopathy Edecio Cunha-Neto ; Luciana G Nogueira; Priscila C Teixeira; Rajendranath Ramasawmy; Sandra A Drigo; Anna Carla Goldberg; Simone G Fonseca; Angelina M Bilate; Jorge Kalil PAGE: 252-258 | DOI: 10.1590/S0074-02762009000900032

Innate immunity and regulatory T-cells in human Chagas disease: what must be understood? Renato Sathler-Avelar; Danielle Marquete Vitelli-Avelar; Andréa Teixeira-Carvalho; Olindo Assis Martins-Filho PAGE: 246-251 | DOI: 10.1590/S0074-02762009000900031

Molecular mechanisms of Trypanosoma cruzi infection by oral route Nobuko Yoshida PAGE: 101-107 | DOI: 10.1590/S0074-02762009000900015

Morbidity and prognostic factors in chronic chagasic cardiopathy Manoel Otávio C Rocha; Maria Carmo P Nunes; Antonio L Ribeiro PAGE: 159-166 | DOI: 10.1590/S0074-02762009000900022

Paleoparasitology of Chagas disease - A review Adauto Araújo ; Ana Maria Jansen; Karl Reinhard; Luiz Fernando Ferreira PAGE: 9-16 | DOI: 10.1590/S0074-02762009000900004

Perspectives of vaccination in Chagas disease revisited Erney Plessmann Camargo PAGE: 275-280 | DOI: 10.1590/S0074-02762009000900036

Proline racemases: insights into Trypanosoma cruzi peptides containing D-proline Nicolas Coatnoan; Armand Berneman; Nathalie Chamond; Paola Minoprio PAGE: 295-300 | DOI: 10.1590/S0074-02762009000900039

Protective immunity against Trypanosoma cruzi Cecilia Parodi; Angel Marcelo Padilla; Miguel Angel Basombrío PAGE: 288-294 | DOI: 10.1590/S0074-02762009000900038

Structural organization of Trypanosoma cruzi Wanderley de Souza PAGE: 89-100 | DOI: 10.1590/S0074-02762009000900014

Sustainability of vector control strategies in the Gran Chaco Region: current challenges and possible approaches Ricardo E Gürtler PAGE: 52-59 | DOI: 10.1590/S0074-02762009000900009

Swimming against the current: genetic vaccination against Trypanosoma cruzi infection in mice Mauricio M Rodrigues ; Bruna C de Alencar; Carla Claser; Fanny Tzelepis; Eduardo L Silveira; Filipe A Haolla; Mariana R Dominguez; José Ronnie Vasconcelos PAGE: 281-287 | DOI: 10.1590/S0074-02762009000900037

Sylvatic triatominae: a new challenge in vector control transmission Felipe Guhl; Nestor Pinto; Germán Aguilera PAGE: 71-75 | DOI: 10.1590/S0074-02762009000900012

The BENEFIT trial: testing the hypothesis that trypanocidal therapy is beneficial for patients with chronic Chagas heart disease J Antonio Marin-Neto ; Anis Rassi Jr; Alvaro Avezum Jr; Antonio C Mattos; Anis Rassi PAGE: 319-324 | DOI: 10.1590/S0074-02762009000900042

The effects of nitric oxide on the immune system during Trypanosoma cruzi infection Fredy RS Gutierrez; Tiago WP Mineo; Wander R Pavanelli; Paulo MM Guedes; João S Silva PAGE: 236-245 | DOI: 10.1590/S0074-02762009000900030

The importance of apoptosis for immune regulation in Chagas disease George A DosReis; Marcela F Lopes PAGE: 259-262 | DOI: 10.1590/S0074-02762009000900033

The utility of anti-trypomastigote lytic antibodies for determining cure of Trypanosoma cruzi infections in treated patients: an overview and perspectives Antoniana Ursine Krettli PAGE: 142-151 | DOI: 10.1590/S0074-02762009000900020

Therapy, diagnosis and prognosis of chronic Chagas disease: insight gained in Argentina Sergio Sosa-Estani ; Rodolfo Viotti; Elsa Leonor Segura PAGE: 167-180 | DOI: 10.1590/S0074-02762009000900023

Trypanosoma cruzi: ancestral genomes and population structure Sérgio DJ Pena; Carlos Renato Machado; Andréa Mara Macedo PAGE: 108-114 | DOI: 10.1590/S0074-02762009000900016

Two approaches to discovering and developing new drugs for Chagas disease JH McKerrow; PS Doyle; JC Engel; LM Podust; SA Robertson; R Ferreira; T Saxton; M Arkin; ID Kerr; LS Brinen; CS Craik PAGE: 263-269 | DOI: 10.1590/S0074-02762009000900034

Usefulness of PCR-based assays to assess drug efficacy in Chagas disease chemotherapy: value and limitations Constança Carvalho Britto PAGE: 122-135 | DOI: 10.1590/S0074-02762009000900018

Viability study of a multiplex diagnostic platform for Chagas disease Leonardo Foti; Bruna de Paula Fonseca e Fonseca; Lilian Dias Nascimento; Christiane de Fatima Silva Marques; Edmilson Domingos da Silva; Cesar Augusto Barros Duarte; Christian M Probst; Samuel Goldenberg; Antônio Gomes Pinto; Marco Aurélio Krieger PAGE: 136-141 | DOI: 10.1590/S0074-02762009000900019

Wild Triatoma infestans, a potential threat that needs to be monitored François Noireau PAGE: 60-64 | DOI: 10.1590/S0074-02762009000900010

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