Memórias do Instituto Oswaldo Cruz

A clinical trial for uniform multidrug therapy for leprosy patients in Brazil: rationale and design Gerson Oliveira Penna ; Maria Araci de Andrade Pontes; Rossilene Cruz; Heitor de Sá Gonçalves; Maria Lúcia Fernandes Penna; Samira Bührer-Sékula PAGE: 22-27 | DOI: 10.1590/S0074-02762012000900005

Association analysis of human leukocyte antigen class II (DRB1) alleles with leprosy in individuals from São Luís, state of Maranhão, Brazil Rita da Graça Carvalhal Frazão Corrêa ; Dorlene Maria Cardoso de Aquino; Arlene de Jesus Mendes Caldas; Humberto de Oliveira Serra; Fábio França Silva; Maxwellem de Jesus Costa Ferreira; Elton Jonh Freitas Santos; Emygdia Rosa Rêgo Barros Pires Leal Mesquita PAGE: 150-155 | DOI: 10.1590/S0074-02762012000900022

Brazilian clinical trial of uniform multidrug therapy for leprosy patients - the correlation between clinical disease types and adverse effects Heitor de Sá Gonçalves ; Maria Araci de Andrade Pontes; Samira Bührer-Sékula; Rossilene Cruz; Paulo Cesar Almeida; Maria Elisabete Amaral de Moraes; Gerson Oliveira Penna PAGE: 74-78 | DOI: 10.1590/S0074-02762012000900013

Characteristics of leprosy diagnosed through the surveillance of contacts: a comparison with index cases in Rio de Janeiro, 1987-2010 Mariana de Andrea Hacker; Nadia Cristina Duppre; José Augusto Costa Nery; Anna Maria Sales; Euzenir Nunes Sarno PAGE: 49-54 | DOI: 10.1590/S0074-02762012000900009

Comparison of two rapid tests for anti-phenolic glycolipid-I serology in Brazil and Nepal Mariane Martins de Araújo Stefani; Adriano Badotti Grassi; Lucas Henrique Sampaio; Ana Lúcia Osório Maroclo de Sousa; Maurício Barcelos Costa; Pauline Scheelbeek; Kapil D Neupane; Deanna A Hagge; Murdo Macdonald; Sang-Nae Cho; Linda Oskam; Samira Bührer-Sékula PAGE: 124-131 | DOI: 10.1590/S0074-02762012000900019

Cutaneous lesions sensory impairment recovery and nerve regeneration in leprosy patients Ximena Illarramendi; Emanuel Rangel; Alice Machado Miranda; Ana Claudia Ribeiro de Castro; Giselle de Oliveira Magalhães; Sérgio Luiz Gomes Antunes PAGE: 68-73 | DOI: 10.1590/S0074-02762012000900012

Deciphering the contribution of lipid droplets in leprosy: multifunctional organelles with roles in Mycobacterium leprae pathogenesis Katherine Antunes de Mattos; Euzenir Nunes Sarno; Maria Cristina Vidal Pessolani; Patricia T Bozza PAGE: 156-166 | DOI: 10.1590/S0074-02762012000900023

Differential expression of the costimulatory molecules CD86, CD28, CD152 and PD-1 correlates with the host-parasite outcome in leprosy Maria de Lourdes Palermo; Maria Ângela Bianconcini Trindade; Alberto José da Silva Duarte; Camila Rodrigues Cacere; Gil Benard PAGE: 167-173 | DOI: 10.1590/S0074-02762012000900024

Erythema multiforme in leprosy Alice Machado Miranda ; Sérgio Luiz Gomes Antunes; José Augusto Costa Nery; Anna Maria Sales; Mario José dos Santos Pereira; Euzenir Nunes Sarno PAGE: 34-42 | DOI: 10.1590/S0074-02762012000900007

Genetics of leprosy reactions: an overview Vinicius Fava; Marianna Orlova; Aurélie Cobat; Alexandre Alcaïs; Marcelo Mira; Erwin Schurr PAGE: 132-142 | DOI: 10.1590/S0074-02762012000900020

Genotyping of Mycobacterium leprae present on Ziehl-Neelsen-stained microscopic slides and in skin biopsy samples from leprosy patients in different geographic regions of Brazil Amanda Nogueira Brum Fontes; Harrison Magdinier Gomes; Marcelo Ivens de Araujo; Edson Cláudio Araripe de Albuquerque; Ida Maria Foschiani Dias Baptista; Maria Manuela da Fonseca Moura; Denise Silva Rezende; Maria Cristina Vidal Pessolani; Flávio Alves Lara; Maria Araci de Andrade Pontes; Heitor de Sá Gonçalves; Norma Lucena-Silva; Euzenir Nunes Sarno; Varalakshmi D Vissa; Patrick J Brennan; Philip Noel Suffys PAGE: 143-149 | DOI: 10.1590/S0074-02762012000900021

Hansen's disease: a vanishing disease? Sinésio Talhari; Maria Aparecida de Faria Grossi; Maria Leide WDR de Oliveira; Bernardo Gontijo; Carolina Talhari ; Gerson Oliveira Penna PAGE: 13-16 | DOI: 10.1590/S0074-02762012000900003

High rates of undiagnosed leprosy and subclinical infection amongst school children in the Amazon Region Josafá Gonçalves Barreto; Layana de Souza Guimarães; Marco Andrey Cipriani Frade; Patricia Sammarco Rosa; Claudio Guedes Salgado PAGE: 60-67 | DOI: 10.1590/S0074-02762012000900011

Historic aspects of human susceptibility to leprosy and the risk of conjugal transmission M Patricia Joyce PAGE: 17-21 | DOI: 10.1590/S0074-02762012000900004

Identification of serological biomarkers of infection, disease progression and treatment efficacy for leprosy John S Spencer; Malcolm S Duthie; Annemieke Geluk; Marivic F Balagon; Hee Jin Kim; William H Wheat; Delphi Chatterjee; Mary Jackson; Wei Li; Jade N Kurihara; Armi Maghanoy; Irene Mallari; Paul Saunderson; Patrick J Brennan; Hazel M Dockrell PAGE: 79-89 | DOI: 10.1590/S0074-02762012000900014

Increased hepcidin expression in multibacillary leprosy Vânia Nieto Brito de Souza; Tatiana Salles de Souza Malaspina; Ana Paula Campanelli; Cássio Ghidella; Somei Ura; Dirceu Dalpino; Dejair Caitano do Nascimento; Ana Carla Pereira Latini PAGE: 183-189 | DOI: 10.1590/S0074-02762012000900026

Insights from animal models on the immunogenetics of leprosy - A review Linda B Adams; Maria T Pena; Rahul Sharma; Deanna A Hagge; Erwin Schurr; Richard W Truman PAGE: 197-208 | DOI: 10.1590/S0074-02762012000900028

Lepromatous leprosy patients produce antibodies that recognise non-bilayer lipid arrangements containing mycolic acids Isabel Baeza; Carlos Wong-Baeza; Esther Valerdi; Jeanet Serafin-Lopez; Miguel Ibáñez; Sergio Estrada-Parra; Carlos Wong; Iris Estrada-Garcia PAGE: 95-103 | DOI: 10.1590/S0074-02762012000900016

Leprosy frequency in the world, 1999-2010 Maria Lúcia Fernandes Penna; Gerson Oliveira Penna PAGE: 3-12 | DOI: 10.1590/S0074-02762012000900002

Leprosy, a neglected disease that causes a wide variety of clinical conditions in tropical countries Norma Tiraboschi Foss; Ana Carolina Fragoso Motta PAGE: 28-33 | DOI: 10.1590/S0074-02762012000900006

Mycobacterial laminin-binding histone-like protein mediates collagen-dependent cytoadherence André Alves Dias; Dominique Raze; Cristiana Soares de Lima; Maria Angela de Melo Marques; Hervé Drobecq; Anne-Sophie Debrie; Michelle Lopes Ribeiro-Guimarães; Franck Biet; Maria Cristina Vidal Pessolani PAGE: 174-182 | DOI: 10.1590/S0074-02762012000900025

Mycobacterium leprae in six-banded (Euphractus sexcinctus) and nine-banded armadillos (Dasypus novemcinctus) in Northeast Brazil Cristiane Cunha Frota; Luana Nepomuceno Costa Lima; Adalgiza da Silva Rocha; Philip Noel Suffys; Benedito Neilson Rolim; Laura Cunha Rodrigues; Maurício Lima Barreto; Carl Kendall; Ligia Regina Sansigolo Kerr PAGE: 209-213 | DOI: 10.1590/S0074-02762012000900029

Mycobacterium leprae virulence-associated peptides are indicators of exposure to M. leprae in Brazil, Ethiopia and Nepal Kidist Bobosha; Sheila Tuyet Tang; Jolien J van der Ploeg-van Schip; Yonas Bekele; Marcia VSB Martins; Ole Lund; Kees LMC Franken; Saraswoti Khadge; Maria Araci de Andrade Pontes; Heitor de Sá Gonçalves: Jemal Hussien; Pratibha Thapa: Chhatra B Kunwar; Deanna A Hagge; Abraham Aseffa; Maria Cristina Vidal Pessolani; Geraldo MB Pereira; Tom HM Ottenhoff; Annemieke Geluk PAGE: 112-123 | DOI: 10.1590/S0074-02762012000900018

Serologic follow-up of IgG responses against recombinant mycobacterial proteins ML0405, ML2331 and LID-1 in a leprosy hyperendemic area in Venezuela Elsa Rada; Malcolm S Duthie; Steven G Reed; Nacarid Aranzazu; Jacinto Convit PAGE: 90-94 | DOI: 10.1590/S0074-02762012000900015

Seroreactivity to new Mycobacterium leprae protein antigens in different leprosy-endemic regions in Brazil Emerith Mayra Hungria; Regiane Morillas de Oliveira; Ana Lúcia Osório Maroclo de Souza; Maurício Barcelos Costa; Vânia Nieto Brito de Souza; Eliane Aparecida Silva; Fátima Regina Vilani Moreno; Maria Esther Salles Nogueira; Maria Renata Sales Nogueira Costa; Sônia Maria Usó Ruiz Silva; Samira Bührer-Sékula; Steven G Reed; Malcolm S Duthie; Mariane Martins de Araújo Stefani PAGE: 104-111 | DOI: 10.1590/S0074-02762012000900017

The potential for vaccination in leprosy elimination: new tools for targeted interventions Malcolm S Duthie; Paul Saunderson; Steven G Reed PAGE: 190-196 | DOI: 10.1590/S0074-02762012000900027

The role of human T cell lymphotrophic virus type 1, hepatitis B virus and hepatitis C virus coinfections in leprosy Paulo Roberto Lima MachadoI, II, +; Warren D JohnsonIII; Marshall J GlesbyIV PAGE: 43-48 | DOI: 10.1590/S0074-02762012000900008

Unveiling healthy carriers and subclinical infections among household contacts of leprosy patients who play potential roles in the disease chain of transmission Sérgio Araújo; Janaína Lobato; Érica de Melo Reis; Dulcinéa Oliveira Bernardes Souza; Maria Aparecida Gonçalves; Adeilson Vieira Costa; Luiz Ricardo Goulart ; Isabela Maria Bernardes Goulart PAGE: 55-59 | DOI: 10.1590/S0074-02762012000900010

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107 (Suppl.I) December 2012

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107 (Suppl.I) December 2012

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