Instructions to authors

The Memórias' content is freely accessible to readers and no publication fees are charged to authors. The Memórias do Instituto Oswaldo Cruz has decided to simplify the requirements regarding the format of submitted manuscripts. From now on, all manuscripts  may be submitted in any text format as long as the common subdivision of scientific articles are followed, e.g. introduction, materials and methods, results, discussion and  references.  For Reviews and Perspectives articles, authors may use the sections that best suit the structure and content of the proposed manuscript. All manuscripts should  contain, besides the title and abstract, full details of authors and institutions, acknowledgements of any technical or financial assistance as well as state any conflicts of interest. This flexible text format will be used for the initial analysis and peer review. If the manuscript is accepted, authors will be requested to edit the text in accordance with the publication style of the Memorias."

Upon acceptance, the manuscript should be arranged in the following format:

The manuscript should be prepared using standard word processing software and should be printed (font size 12) double-spaced throughout the text, figure captions, and references, with margins of at least 3 cm. The figures should come in the extension tiff, with a minimum resolution of 300 dpi. Tables and legends to figures must be submitted all together in a single file. Figures must be uploaded separately as supplementary file.

Title: with up to 250 characters

Author's names: without titles or graduations

Institutional affiliations: full address of the all authors

Abstracts: Provide an abstract up to 200 words. Abstracts of research articles should be structured into 5 sections as follows: BACKGROUND, OBJECTIVES, METHODS, FINDINGS and MAIN CONCLUSIONS, each section addressing respectively the problem, the aim of the study, the main methodological approach, the most important findings and the conclusions of the study.

Key words: 3-6 items must be provided. Terms from the Medical Subject Headings (Mesh) list of Index Medicus should be used.

Sponsorships: indicate the sources of financial support.

Introduction: should set the purpose of the study, give a brief summary (not a review) of previous relevant work, and state what new advance has been made in the investigation. It should not include data or conclusions from the work being reported.

Materials and Methods: should give full and clear information to permit the study to be repeated by others. Standard techniques need only be referenced. However if a modification has been done in a standard protocol, it must be clearly described.

Ethics: when reporting experiments on human subjects, indicate whether the procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional or regional) and with the Helsinki Declaration of 1975, as revised in 1983. When reporting experiments on animals, indicate whether the institution's or a national research council's guide for, or any national law on the care and use of laboratory animals was followed. In case the research work is making use of natural resources (plant, microorganisms, biodiversity samples) authors must provide a statement that the research work is compliant with the national regulations on this subject.

Results: should be a concise account of the new information discovered, with the least personal judgement. Do not repeat in the text data already described in tables and illustrations.

Discussion: should emphasize the relevance of the new information and relate the new findings to existing knowledge. Only unavoidable citations should be included.

Acknowledgements: should list and give full credit to all of those (apart from authors) who has helped the achievement of the research work (including the funding organizations).

Conflict of Interests: authors must disclose any conflict of interest related to their research work.

Author's contribution: state each author's contribution to the research work.

Must be accurate. Only citations that appear in the text should be referenced. Articles in Preprint Servers can be cited only if a DOI is provided. Unpublished papers, unless accepted for publication, should not be cited. Work accepted for publication should be referred to as "in press" and either the journal link for the accepted manuscript or a letter of acceptance of the journal must be provided. Unpublished data should only be cited in the text as "unpublished observations", and a letter of permission from the author must be provided. The references at the end of the paper should be listed in numerical order, and in the same order in which they are cited in text. CLICK HERE [+]

To assure your references is published as requested, please send archives without Mendeley Hyperlink or similar. References created with edition marks will cause improper corrections during editing process, causing delays.


Should be abbreviated according to the the NLM Title Abbreviation for Journals currently indexed in MEDLINE. For details, please visit

A number is allocated to a source in the order in which it is cited in the text. If the source is referred to again, the same number is used.

Use superscript Arabic numerals (1,2,3,4,5,6,7,8,9) inside of curved brackets.

List each reference number separated by comma, or by dash for a sequence of consecutive numbres. There should be no spaces between commas or dashes. Ex.: (1,3,6-8).

The in-text citation is placed immediately after the text, which refers to the source being cited.
Ex.: These observations were consistent with those made in Venezuela, Brazil, and British Guyana.(1-4)

The author’s name can also be included in the text.
Ex.: The method for quantifying egg viability was adapted from Farnesi et al.(1)


Journal article
Chagas C, Villela E. Forma cardíaca da tripanosomiase americana. Mem Inst Oswaldo Cruz. 1922; 14(1): 05-61.

Book and Thesis
Forattini OP. Entomologia médica. Psychodidae, Phlebotominae, Leishmaniose, Bartonelose. Vol. IV. São Paulo: Edgard Blucher; 1973. 658 pp.

Morel CM. Genes and antigens of parasites. A laboratory manual. 2nd ed. Rio de Janeiro: Fiocruz; 1983. xxii + 580 pp.

Mello-Silva CC. Controle alternativo e alterações fisiológicas em Biomphalaria glabrata (Say, 1818), hospedeiro intermediário de Schistosoma mansoni Sambom, 1907 pela ação do látex de Euphorbia splendens var. hislopii N.E.B (Euphorbiaceae) [PhD Thesis]. Seropédica: Universidade Federal Rural do Rio de Janeiro; 2005. 85 pp.

Chapter in book
Cruz OG. The prophylaxis of malaria in central and southern Brasil. In: Ross R, The prevention of malaria. London: John Murray; 1911. 390-8.

Journal article on the Internet
Abood S. Quality improvement initiative in nursing homes: the ANA acts in an advisory role. Am J Nurs [Internet]. 2002 [cited 2002 Aug 12]; 102(6). Available from:

Monograph on the Internet
Foley KM, Gelband H, editors. Improving palliative care for cancer [monograph] [Internet]. Washington: National Academy Press; 2001 [cited 2002 Jul 9]. Available from:

Homepage/Web site [homepage on the Internet]. New York: Association of Cancer Online Resources, Inc.; c2000-01 [updated 2002 May 16; cited 2002 Jul 9]. Available from:

Part of a homepage/Web site
American Medical Association [homepage on the Internet]. Chicago: The Association; c1995-2002 [updated 2001 Aug 23; cited 2002 Aug 12]. AMA Office of Group Practice Liaison; [about 2 screens]. Available from:


Open database
Who's Certified [database on the Internet]. Evanston (IL): The American Board of Medical Specialists. c2000 - [cited 2001 Mar 8]. Available from:

Closed database
Jablonski S. Online Multiple Congenital Anomaly/Mental Retardation (MCA/MR) Syndromes [Internet]. Bethesda (MD): National Library of Medicine (US). c1999 [updated 2001 Nov 20; cited 2002 Aug 12]. Available from:

Part of a database on the Internet
MeSH Browser [Internet]. Bethesda (MD): National Library of Medicine (US); 2002. Meta-analysis; 2003 [cited 2003 Jun 10]; [about 3 p.]. Available from:

Figures and tables must be understandable without reference to the text

Figures: presented in tiff format with a minimum of 300 dpi.  Photographs must be sharply focused, well contrasted, and if mounted onto a plate, the figures should be numbered consecutively with Arabic numbers. Magnification must be indicated by a line or bar in the figure, and referenced, if necessary in the caption (e.g., bar = 1 mm). Plates and line figures should either fit one column (8 cm) or the full width (16.5 cm) of the page and should be shorter than the page length to allow inclusion of the legend. Letters and numbers on figures should be of a legible size upon reduction or printing. A colour photograph or a related illustration is used in social media of the Journal (Twitter, Instagram and Facebook) for brief information about the content of accepted articles. Authors are invited to submit illustrations with legends from their manuscript for dissemination in social media.

Tables: should supplement, not duplicate, the text and should be numbered with Roman numerals. A short descriptive title should appear above each table, with any explanations or footnotes (identified with a, b, c, etc.) below.

Supplemental material: refers to files which authors supply for publication alongside their article. They should generally be additional pieces to the article that could not be included in the issue, such as appendices, spreadsheets, tables, figures that is impossible to produce within the article. These files will be sent to reviewers for peer review, along with the article’s main files.

We recommend that Supplementary files be in the following format:
- Excel or any spreadsheet should be uploaded in PDF format or provide link to access files
- Supplementary figures with five or more pieces please provide a PDF file with as many figures as possible.

We recommend providing small size files for quick download.

Review/Perspective: articles in “review/perspective” format are accepted only by means of invitations made by the editor or associated editors.

Alternative format: manuscripts may be submitted following the "Uniform Requirements for Manuscripts Submitted to Biomedical Journals" produced by the International Committee of Medical Journal Editors also known as the Vancouver Style. In this case, authors should follow the guidelines in the fifth edition (Annals of Internal Medicine 1997; 126: 36-47, or at the website and will be responsible for modifying the manuscript where it differs from the instructions given here, if the manuscript is accepted for publication.
Authors should also follow the Uniform Requirements for any guidelines that are omitted in these Instructions.

Once a paper is accepted for publication, no changes to the original manuscript will be allowed except for minor corrections.

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